Mickaël Mathieu Ménager
  • Group leader, Institut Imagine
Research fields
  • Immunology
Personal information



Lab information

Mickael Menager Lab

Research focus

Inflammatory diseases, Transcriptomic Networks, HIV


Ménager MM, Littman DR. Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells. Cell. (2016) Jan 27. pii: S0092-8674(15)01700-6. doi: 10.1016/j.cell.2015.12.036. [Epub ahead of print]. PMID:26830877

Côte M*, Ménager MM*, Burgess A, Mahlaoui N, Picard C, Schaffner C, Al-Manjomi F, Al-Harbi M, Alangari A, Le Deist F, Gennery AR, Prince N, Cariou A, Nitschke P, Blank U, El-Ghazali G, Ménasché G, Latour S, Fischer A, de Saint Basile G. Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. J Clin Invest. (2009) Dec;119(12):3765-73. doi: 10.1172/JCI40732. Epub 2009 Nov 2. PMID: 19884660 (* Co-first-authors).

Ménasché G*, Ménager MM*, Lefebvre JM, Deutsch E, Athman R, Lambert N, Mahlaoui N, Court M, Garin J, Fischer A, de Saint Basile G. A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion. Blood. (2008) Dec 15;112(13):5052-62. Epub 2008 Sep 23. PMID: 18812475. (* Co-first-authors).

Ménager MM, Ménasché G, Romao M, Knapnougel P, Ho CH, Garfa M, Raposo G, Feldmann J, Fischer A, de Saint Basile G. Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol. (2007) Mar;8(3):257-67. Epub 2007 Jan 21.PMID: 17237785
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