Marie Sissler Université de Bordeaux, CNRS, IECB Pessac
1 protocol

Stéphanie Durrieu-Gaillard Institut Européen de Chimie et Biologie, U1212 Inserm/UMR5320 CNRS, Université de Bordeaux, CNRS, IECB, Pessac
1 protocol

Philippe Giegé Université de Strasbourg
1 protocol

Florent Waltz Université de Bordeaux
1 protocol

Yaser Hashem
  • Faculty, Université de Bordeaux, Inserm, IECB Pessac
Research focus
  • Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.
  • 2 Author merit

Lab information

Hashem Lab
http://hashem-lab.fr

Publications

2 Protocols published
Purification of Mitochondrial Ribosomal Complexes from Trypanosoma cruzi and Leishmania tarentolae for Cryo-EM Analysis
Authors:  Stéphanie Durrieu-Gaillard, Marie Sissler and Yaser Hashem, date: 05/20/2022, view: 917, Q&A: 1

Kinetoplastids are unicellular eukaryotic parasites responsible for human pathologies such as Chagas disease, sleeping sickness or Leishmaniasis, caused by Trypanosoma cruzi, Trypanosoma brucei, and various Leishmania spp., respectively. They harbor

...
Purification and Cryo-electron Microscopy Analysis of Plant Mitochondrial Ribosomes
Authors:  Florent Waltz, Philippe Giegé and Yaser Hashem, date: 08/05/2021, view: 1699, Q&A: 0

Plants make up by far the largest part of biomass on Earth. They are the primary source of food and the basis of most drugs used for medicinal purposes. Similarly to all eukaryotes, plant cells also use mitochondria for energy production. Among

...
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