Karl Kuchler Medical University of Vienna, Center for Medical Biochemistry, Max Perutz Labs Vienna, Campus Vienna Biocenter, A-1030 Vienna
6 protocols

Sabrina Jenull Medical University Vienna, Max F. Perutz Laboratories, Department of Medical Biochemistry, Austria
1 protocol

Miha Tome Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia
1 protocol

Michael Tscherner Medical University of Vienna
4 protocols

Fabian Istel
  • Medical University Vienna, Max F. Perutz Laboratories, Department of Medical Biochemistry, Austria
Research focus
  • Microbiology
  • 4 Author merit


M.S, Medical University of Vienna, Vienna, 2010

Current position

Ph.D student, Medical University of Vienna, Vienna (since 2010)


  1.  Ryan, O., Shapiro, R. S., Kurat, C. F., Mayhew, D., Baryshnikova, A., Chin, B., Lin, Z. Y., Cox, M. J., Vizeacoumar, F., Cheung, D., Bahr, S., Tsui, K., Tebbji, F., Sellam, A., Istel, F., Schwarzmuller, T., Reynolds, T. B., Kuchler, K., Gifford, D. K., Whiteway, M., Giaever, G., Nislow, C., Costanzo, M., Gingras, A. C., Mitra, R. D., Andrews, B., Fink, G. R., Cowen, L. E. and Boone, C. (2012). Global gene deletion analysis exploring yeast filamentous growth. Science 337(6100): 1353-1356.
  2.  Schwarzmuller, T., Ma, B., Hiller, E., Istel, F., Tscherner, M., Brunke, S., Ames, L., Firon, A., Green, B., Cabral, V., Marcet-Houben, M., Jacobsen, I. D., Quintin, J., Seider, K., Frohner, I., Glaser, W., Jungwirth, H., Bachellier-Bassi, S., Chauvel, M., Zeidler, U., Ferrandon, D., Gabaldon, T., Hube, B., d'Enfert, C., Rupp, S., Cormack, B., Haynes, K. and Kuchler, K. (2014). Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes. PLoS Pathog 10(6): e1004211.
  3. Zwolanek, F., Riedelberger, M., Stolz, V., Jenull, S., Istel, F., Koprulu, A. D., Ellmeier, W. and Kuchler, K. (2014). The non-receptor tyrosine kinase Tec controls assembly and activity of the noncanonical caspase-8 inflammasome. PLoS Pathog 10(12): e1004525.
  4.  Lackner, M., Tscherner, M., Schaller, M., Kuchler, K., Mair, C., Sartori, B., Istel, F., Arendrup, M. C. and Lass-Florl, C. (2014). Positions and numbers of FKS mutations in Candida albicans selectively influence in vitro and in vivo susceptibilities to echinocandin treatment. Antimicrob Agents Chemother 58(7): 3626-3635.
4 Protocols published
Phenotypic Profiling of Candida glabrata in Liquid Media
Authors:  Fabian Istel, Miha Tome, Sabrina Jenull and Karl Kuchler, date: 04/05/2017, view: 9686, Q&A: 0
Here, we describe a method for a large-scale liquid screening approach in C. glabrata. This liquid media method offers several distinct advantages over solid media approaches. This includes growth measurement on a plate reader instead of ...
Large-scale Phenotypic Profiling of Gene Deletion Mutants in Candida glabrata
Authors:  Fabian Istel, Tobias Schwarzmüller, Michael Tscherner and Karl Kuchler, date: 07/20/2015, view: 9377, Q&A: 0
Here, we describe a method enabling the phenotypic profiling of genome-scale deletion collections of fungal mutants to detect phenotypes for various stress conditions. These stress conditions include among many others antifungal drug susceptibility, ...
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