Lab Protocol Hub

13 Protocols | Gladstone Institutes and University of California, San Francisco | Cell Biology

Mucosal transmission of HIV is a major force driving expansion of the global AIDS epidemic. Understanding the initial events in the establishment of infection in a new host is key to developing an effective vaccine and microbicides.Our main focus is to understand HIV transmission: what cells HIV initially ...

36 Protocols | The Buck Institute, USA | Cell Biology

Understanding the role of nutrition and energy metabolism in lifespan and diseaseThe overall goal of the Kapahi laboratory is to understand how an organism responds to nutrient status to influence health and disease. We utilize worms, flies and mice as model systems to understand how nutrients influence ...

11 Protocols | Immunity, Transplantation & Infection, School of Medicine, Stanford University, Stanford

Holden Maecker is a Professor of Microbiology and Immunology at Stanford University.  His research group is focused on cellular immune responses to chronic pathogens and cancer, and the correlation of those responses with immune protection.The group has published a number of papers on this topic, both ...

7 Protocols | Stanford University | Molecular Biology

We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to cancer and other human diseases. Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs ...

5 Protocols | Stanford University | Immunology

The Utz lab is part of the Department of Medicine, Division of Immunology at Stanford University School of Medicine. We focus on the normal immune system and how it differs from the immune system of patients with immunodeficiency disorders, infections, and autoimmune diseases. Autoimmune diseases being ...

6 Protocols | Stanford University | Mechanobiology

We are interested in elucidating the complex mechanical properties of cells and the extracellular matrix, and in turn, investigating how these mechanical properties and other mechanical cues play a role in important biological processes such as cancer progression, stem cell differentiation, or cell division. ...

7 Protocols | Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Science | Plant Science

Group of Plant-Fungal Interaction and Plant Reproductive Biology led by Prof. Weihua Tang is a member of National Lab of Plant Molecular Genetics at Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences. Pollen tubes and pathogenic fungal hyphae are two very different types of ...

4 Protocols | Stanford University | Molecular Biology

The regulation of chromatin structure is essential for all eukaryotic organisms. Our research interests are to determine the contribution of chromatin to mechanisms that maintain genomic integrity and metabolic homeostasis in the context of disease and development.  We utilize a varied experimental ...

1 Protocol | Stanford University | Genetics

Protein folding is critically important for all life, from microbes to man. A bafflingly diverse set of cellular mechanisms has evolved to coordinate this exquisitely sensitive process. Not unexpectedly, problems in protein folding are the root cause of many of the most devastating diseases, which represent ...

8 Protocols | Department of Biological Sciences, UMBC, US, US, | Microbiology

In the Green Lab, we are broadly interested in the fundamental molecular mechanisms governing the epigenetic regulation of the genome and its integration with cellular signaling pathways. In particular, we aim to understand how post-translational modifications of proteins regulate critical biological ...