Despina Smirlis Microbiology, HELLENIC PASTEUR INSTITUTE, Greece
2 protocols
Abhijit Kale Deciduous Therapeutics
10 protocols

Adam Idoine Carnegie Institution
16 protocols

Amit Dey International Centre for Genetic Engineering and Biotechnology
17 protocols

Anu Minhas university institute if engineering and technology (uiet), panjab university chandigarh
2 protocols

Editor
Alexandros Alexandratos
  • Research associate, National and Kapodistrian University of Athens
Research focus
  • Microbiology
  • Proteomics, Signaling, Transcriptomics, Gene regulation
  • 1 Author merit

Education

PhD, University of Ioannina, Greece, 2014

Lab information

Skarlatos Dedos Laboratory, Faculty of Biology, National and Kapodistrian University of Athens

Publications

Panagiotis Moulos*, Alexandros Alexandratos*, Ioannis Nellas, Skarlatos Dedos. (2018) Refining a steroidogenic model: an analysis of RNA-seq datasets from insect prothoracic glands. BMC Genomics, 19 (1): 537 (*Shared Authorship)

Alexandros Alexandratos*, Panagiotis Moulos*, Ioannis Nellas, Konstantinos Mavridis, Skarlatos Dedos. (2016) Reassessing ecdysteroidogenic cells from the cell membrane receptors’ perspective. Scientific Reports, 6, 20229 (*Shared Authorship)

Antonia Efstathiou, Nicolas Gaboriaud-Kolar, Despina Smirlis, Vassilios Myrianthopoulos, Konstantina Vougogianopoulou, Alexandros Alexandratos, Marina Kritsanida, Emmanuel Mikros, Ketty Soteriadou, Alexios-Leandros Skaltsounis. (2014) An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial glycogen synthase kinase-3 over leishmanial cdc2-related protein kinase 3. Parasites & Vectors, 7, 234

Alexandros Alexandratos, Joachim Clos, Martina Samiotaki, Antonia Efstathiou, George Panayotou, Ketty Soteriadou, Despina Smirlis. (2013) The loss of virulence of histone H1 overexpressing Leishmania donovani parasites is directly associated with a reduction of HSP83 rate of translation. Molecular Microbiology, 88 (5), 1015-1031


Dimitra Kovala-Demertzi, Athanassios Papageorgiou, Leuteris Papathanasis, Alexandros Alexandratos, Panagiotis Dalezis, John R. Miller, Mavroudis A. Demertzis. (2009) In vitro and in vivo antitumor activity of platinum(II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N(4)-position: Synthesis, spectroscopic study and crystal structure of platinum(II) complexes with thiosemicarbazones, potential anticancer agents. European Journal of Medicinal Chemistry, 44 (3), 1296-1302

Dimitra Kovala-Demertzi, Alexandros Alexandratos, Athanassios Papageorgiou, Paras Nath Yadav, Panagiotis Dalezis, Mavroudis A. Demertzis. (2008) Synthesis, characterization, crystal structures, in vitro and in vivo antitumor activity of palladium(II) and zinc(II) complexes with 2-formyl and 2-acetyl pyridine N(4)-1-(2-pyridyl)-piperazinyl thiosemicarbazone. Polyhedron, 27 (13), 2731-2738
1 Protocol published
Protein Sample Preparation for Proteomic Analysis in Leishmania donovani
Authors:  Alexandros Alexandratos and Despina Smirlis, date: 03/05/2014, view: 9127, Q&A: 0
Leishmania is a genus of trypanosomatid protozoa and is the parasite responsible for the disease leishmaniasis. These protozoa, regulate their gene expression in an atypical way, compared to other higher eukaryotes. The regulation of gene ...
12 Protocols reviewed
Production, quantification, and infection of Amazonian Phlebovirus (Bunyaviridae)

Phlebotomine vectors, sand flies of the order Diptera, are known to transmit Leishmania parasites as well as RNA viruses (arboviruses) to humans. The arbovirus, Icoaraci Phlebovirus (BeAN 24262 - ICOV), used in this study was isolated from Nectomys

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Detection of Membrane Protein Interactions by Cell-based Tango Assays
The Tango assay is a protein-protein interaction assay, in which a transcription factor (rTA) is fused to a membrane-bound protein via a linker that contains a cleavage site for TEV protease, whereas a soluble interaction partner is fused to TEV ...
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36 Protocols edited
Yeast Lipid Extraction and Analysis by HPTLC
Authors:  Dan Li, Zheng-Tan Zhang, Cheng-Wen He and Zhiping Xie, date: 07/05/2021, view: 801, Q&A: 0

The diversity of lipid structures, properties, and combinations in biological tissues makes their extraction and analysis an experimental challenge. Accordingly, even for one of the simplest single-cellular fungi, the budding yeast (Saccharomyces

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Fluorescence-based Heme Quantitation in Toxoplasma Gondii
Authors:  Amy Bergmann and Zhicheng Dou, date: 06/20/2021, view: 839, Q&A: 0

Toxoplasma gondii is a highly prevalent protozoan pathogen throughout the world. As a eukaryotic intracellular pathogen, Toxoplasma ingests nutrients from host cells to support its intracellular growth. The parasites also encode full or partial

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