Despina Smirlis Microbiology, HELLENIC PASTEUR INSTITUTE, Greece
2 protocols
Abhijit Kale LevitasBio
10 protocols

Adam Idoine Carnegie Institution
16 protocols

Alba Blesa Universidad Francisco de Vitoria
39 protocols

Alexander Miethke Cincinnati Childrens Hospital Cincinnati
12 protocols

Editor
Alexandros Alexandratos
  • Research associate, National and Kapodistrian University of Athens
Research focus
  • Microbiology
  • Proteomics, Signaling, Transcriptomics, Gene regulation
  • 1 Author merit

Education

PhD, University of Ioannina, Greece, 2014

Lab information

Skarlatos Dedos Laboratory, Faculty of Biology, National and Kapodistrian University of Athens

Publications

Panagiotis Moulos*, Alexandros Alexandratos*, Ioannis Nellas, Skarlatos Dedos. (2018) Refining a steroidogenic model: an analysis of RNA-seq datasets from insect prothoracic glands. BMC Genomics, 19 (1): 537 (*Shared Authorship)

Alexandros Alexandratos*, Panagiotis Moulos*, Ioannis Nellas, Konstantinos Mavridis, Skarlatos Dedos. (2016) Reassessing ecdysteroidogenic cells from the cell membrane receptors’ perspective. Scientific Reports, 6, 20229 (*Shared Authorship)

Antonia Efstathiou, Nicolas Gaboriaud-Kolar, Despina Smirlis, Vassilios Myrianthopoulos, Konstantina Vougogianopoulou, Alexandros Alexandratos, Marina Kritsanida, Emmanuel Mikros, Ketty Soteriadou, Alexios-Leandros Skaltsounis. (2014) An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial glycogen synthase kinase-3 over leishmanial cdc2-related protein kinase 3. Parasites & Vectors, 7, 234

Alexandros Alexandratos, Joachim Clos, Martina Samiotaki, Antonia Efstathiou, George Panayotou, Ketty Soteriadou, Despina Smirlis. (2013) The loss of virulence of histone H1 overexpressing Leishmania donovani parasites is directly associated with a reduction of HSP83 rate of translation. Molecular Microbiology, 88 (5), 1015-1031


Dimitra Kovala-Demertzi, Athanassios Papageorgiou, Leuteris Papathanasis, Alexandros Alexandratos, Panagiotis Dalezis, John R. Miller, Mavroudis A. Demertzis. (2009) In vitro and in vivo antitumor activity of platinum(II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N(4)-position: Synthesis, spectroscopic study and crystal structure of platinum(II) complexes with thiosemicarbazones, potential anticancer agents. European Journal of Medicinal Chemistry, 44 (3), 1296-1302

Dimitra Kovala-Demertzi, Alexandros Alexandratos, Athanassios Papageorgiou, Paras Nath Yadav, Panagiotis Dalezis, Mavroudis A. Demertzis. (2008) Synthesis, characterization, crystal structures, in vitro and in vivo antitumor activity of palladium(II) and zinc(II) complexes with 2-formyl and 2-acetyl pyridine N(4)-1-(2-pyridyl)-piperazinyl thiosemicarbazone. Polyhedron, 27 (13), 2731-2738
1 Protocol published
Protein Sample Preparation for Proteomic Analysis in Leishmania donovani
Authors:  Alexandros Alexandratos and Despina Smirlis, date: 03/05/2014, view: 9956, Q&A: 0
Leishmania is a genus of trypanosomatid protozoa and is the parasite responsible for the disease leishmaniasis. These protozoa, regulate their gene expression in an atypical way, compared to other higher eukaryotes. The regulation of gene ...
13 Protocols reviewed
Protocol for Initiating and Monitoring Bumble Bee Microcolonies with Bombus impatiens (Hymenoptera: Apidae)
Author:  David M. Lehmann, date: 06/20/2022, view: 1109, Q&A: 0

Populations of some bumble bee species are in decline, prompting the need to better understand bumble bee biology and for assessing the effects of environmental stressors on these important pollinators. Microcolonies have been successfully used for

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Production, quantification, and infection of Amazonian Phlebovirus (Bunyaviridae)

Phlebotomine vectors, sand flies of the order Diptera, are known to transmit Leishmania parasites as well as RNA viruses (arboviruses) to humans. The arbovirus, Icoaraci Phlebovirus (BeAN 24262 - ICOV), used in this study was isolated from Nectomys

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52 Protocols edited
Activity-based Crosslinking to Identify Substrates of Thioredoxin-domain Proteins in Malaria Parasites
Authors:  David W. Cobb, Grace S. Woods and Vasant Muralidharan, date: 02/20/2022, view: 1177, Q&A: 0
Malaria remains a major public health issue, infecting nearly 220 million people every year. The spread of drug-resistant strains of Plasmodium falciparum around the world threatens the progress made against this disease. Therefore, ...
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A Hypersensitive Genetically Encoded Fluorescent Indicator (roGFP2-Prx1) Enables Continuous Measurement of Intracellular H2O2 during Cell Micro-cultivation
Authors:  Veronica Gast, Verena Siewers and Mikael Molin, date: 02/05/2022, view: 1281, Q&A: 0

Hydrogen peroxide (H2O2) is a toxic oxidant produced as a byproduct of several biological processes. At too high levels of hydrogen peroxide cells will experience oxidative stress, leading to a cellular response to decrease its levels and to protect

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