Yang Chen 1 protocol

Guohong Wang 1 protocol

Zheping Cai 1 protocol

扬 陈 1 protocol
Abhijit Kale Buck Institute for Research on Aging
5 protocols

Ehsan Kheradpezhouh Australian National University
8 protocols

Oneil Bhalala Baker Institute
48 protocols

Patrick Ovando-Roche CRISPR Therapeutics
5 protocols

Miao He
  • Faculty, Institute of Brain Science, Fudan University
Research focus
  • Neuroscience
  • Neuronal diversity
    Genetic targeting
    Neural circuit
  • 3 Author merit


Ph.D, Stony Brook University, 2011

Lab information

Miao He Lab


• Paul, A., Crow M., Raudales R., He M., Gillis J., Huang Z. J. Transcriptional architecture of synaptic communication delineates gabaergic neuron identity. Cell 2017; 171(3): 522-539 e520.
• Kim, Y., Yang G. R., Pradhan K., Venkataraju K. U., Bota M., Garcia Del Molino L. C., Fitzgerald G., Ram K., He M., Levine J. M., Mitra P., Huang Z. J., Wang X. J., Osten P. Brain-wide maps reveal stereotyped cell-type-based cortical architecture and subcortical sexual dimorphism. Cell 2017; 171(2): 456-469 e422.
• Lu, J., Tucciarone J., Padilla-Coreano N., He M., Gordon J. A., Huang Z. J. Selective inhibitory control of pyramidal neuron ensembles and cortical subnetworks by chandelier cells. Nat Neurosci 2017; 20(10): 1377-1383.
• Li, J., Wang C., Zhang Z., Wen Y., An L., Liang Q., Xu Z., Wei S., Li W., Guo T., Liu G., Tao G., You Y., Du H., Fu Z., He M., Chen B., Campbell K., Alvarez-Buylla A., Rubenstein J. L., Yang Z. Transcription factors sp8 and sp9 coordinately regulate olfactory bulb interneuron development. Cereb Cortex 2017: 1-17.
• Li, Q., Zhang P., Yu X., Zhao Y., Li Q., Zhang Y., Yang Z., Xie Y., Xue P., Sun S., Jia X., Zhou Z., He M., Zhang Y. Lead transiently promotes granulocyte-macrophage progenitor differentiation and subsequently suppresses common myeloid progenitor differentiation. Toxicol Sci 2017.
• He, M., Tucciarone J., Lee S., Nigro M. J., Kim Y., Levine J. M., Kelly S. M., Krugikov I., Wu P., Chen Y., Gong L., Hou Y., Osten P., Rudy B., Huang Z. J. Strategies and tools for combinatorial targeting of gabaergic neurons in mouse cerebral cortex. Neuron 2016; 91(6): 1228-1243.
• Zhang, Q., Zhang Y., Wang C., Xu Z., Liang Q., An L., Li J., Liu Z., You Y., He M., Mao Y., Chen B., Xiong Z. Q., Rubenstein J. L., Yang Z. The zinc finger transcription factor sp9 is required for the development of striatopallidal projection neurons. Cell Rep 2016; 16(5): 1431-1444.
• Zhou, X., Liu F., Tian M., Xu Z., Liang Q., Wang C., Li J., Liu Z., Tang K., He M., Yang Z. Transcription factors coup-tfi and coup-tfii are required for the production of granule cells in the mouse olfactory bulb. Development 2015; 142(9): 1593-1605.
• Fenno, L. E., Mattis J., Ramakrishnan C., Hyun M., Lee S. Y., He M., Tucciarone J., Selimbeyoglu A., Berndt A., Grosenick L., Zalocusky K. A., Bernstein H., Swanson H., Perry C., Diester I., Boyce F. M., Bass C. E., Neve R., Huang Z. J., Deisseroth K. Targeting cells with single vectors using multiple-feature boolean logic. Nat Methods 2014; 11(7): 763-772.
• Huang, Z. J., Taniguchi H., He M., Kuhlman S. Cre-dependent adeno-associated virus preparation and delivery for labeling neurons in the mouse brain. Cold Spring Harb Protoc 2014; 2014(2): 190-194.
• Huang, Z. J., Taniguchi H., He M., Kuhlman S. Genetic labeling of neurons in mouse brain. Cold Spring Harb Protoc 2014; 2014(2): 150-160.
• Pfeffer, C. K., Xue M., He M., Huang Z. J., Scanziani M. Inhibition of inhibition in visual cortex: The logic of connections between molecularly distinct interneurons. Nat Neurosci 2013; 16(8): 1068-1076.
• He, M., Liu Y., Wang X., Zhang M. Q., Hannon G. J., Huang Z. J. Cell-type-based analysis of microrna profiles in the mouse brain. Neuron 2012; 73(1): 35-48.
• Taniguchi, H., He M., Wu P., Kim S., Paik R., Sugino K., Kvitsiani D., Fu Y., Lu J., Lin Y., Miyoshi G., Shima Y., Fishell G., Nelson S. B., Huang Z. J. A resource of cre driver lines for genetic targeting of gabaergic neurons in cerebral cortex. Neuron 2011; 71(6): 995-1013.
• Qin, B., He M., Chen X., Pei D. Sorting nexin 10 induces giant vacuoles in mammalian cells. J Biol Chem 2006; 281(48): 36891-36896.
• Huang Z.J., Taniquchi H., He M., Kuhlman S. (2011). Chapter 13: Genetic Labeling of Neurons in Mouse Brain. Imaging in Developmental Biology: A Laboratory Manual (Book chapter)
3 Protocols published
Authors:  蔡哲平 , 王国宏 , 陈扬 and 何苗, date: 09/13/2018, view: 1487, Q&A: 0
Caesarean Sectioning and Cross-Fostering of the Mouse
Authors:  Zheping Cai, Guohong Wang, Yang Chen and Miao He, date: 11/20/2018, view: 910, Q&A: 0
A caesarean section is required if the recipient of an embryo transfer or any pregnant mouse has not given birth by the delivery time that is normal for the particular strain. It is commonly used to derive a strain of pathogen-free mice from a ...
1 Protocol reviewed
Induction of Photothrombotic Stroke in the Sensorimotor Cortex of Rats and Preparation of Tissue for Analysis of Stroke Volume and Topographical Cortical Localization of Ischemic Infarct
Authors:  Anna M. Wiersma and Ian R. Winship, date: 05/20/2018, view: 3045, Q&A: 0
The photothrombotic model of stroke is commonly used in research as it allows the ischemic infarct to be targeted to specific regions of the cortex with high reproducibility and well-defined infarct borders. Unlike other models of stroke, ...
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2 Protocols edited
Flip-flop Mediated Conditional Gene Inactivation in Drosophila
Authors:  Sathiya N. Manivannan, Priyanka Pandey and Sonal Nagarkar-Jaiswal, date: 02/05/2019, view: 825, Q&A: 0
Mosaic analysis in Drosophila, an important tool to assess cellular phenotypes of mutants in an otherwise heterozygous background, relies on mitosis. Hence, it cannot be used to inactivate gene function in mitotically inactive, terminally ...
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Embryonic Intravitreous Injection in Mouse
Authors:  Liyuan Cui, Yupu Diao and Jiayi Zhang, date: 07/20/2018, view: 1194, Q&A: 0
Axons of retinal ganglion cells (RGCs) relay visual information from the retina to lateral geniculate nucleus (LGN) and superior colliculus (SC), which are two major image-forming visual nuclei. Wiring of these retinal projections completes before ...
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