Sylvain Baron Cellecta

Home

Archive

About Us

David Paul MRC Laboratory of Molecular Biology
47 protocols

Thirupugal Govindarajan Cincinnati Children's Hospital Medical Center
13 protocols

Reviewer

Sylvain Baron

Cellecta

Research focus

Cancer biology

Reviewer merit
Editor merit

2 Protocols reviewed

Screening Method for CRISPR/Cas9 Inhibition of a Human DNA Virus: Herpes Simplex Virus

Authors: Werner M. Neuhausser, Hyung S. Oh, Pierce Eggan, Magdalena Angelova, Rory Kirchner, Kevin C. Eggan and David M. Knipe, date: 09/05/2020, view: 4064, Q&A: 0

The efficiency of cleavage of individual CRISPR/Cas9-sgRNAs remains difficult to predict based on the CRISPR target sequence alone. Different intracellular environments (dependent on cell type or cell cycle state for example) may affect sgRNA ...

More >

CRISPR/Cas9 + AAV-mediated Intra-embryonic Gene Knocking in Mice

Authors: Naoaki Mizuno, Eiji Mizutani, Hideyuki Sato, Mariko Kasai, Hiromitsu Nakauchi and Tomoyuki Yamaguchi, date: 07/05/2019, view: 4549, Q&A: 0

Intra-embryo genome editing by CRISPR/Cas9 has enabled rapid generation of gene knockout animals. However, large fragment knock-in directly into embryos’ genome is still difficult, especially without microinjection of donor DNA. Viral vectors are ...

More >