Education

Ph.D. in Pharmacology, University of Minnesota, USA

Current position

Chair, Department of Physiology, College of Medicine, Taipei Medical University, Taiwan (2010-present)
Professor, Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan

Publications (since 2009)

1. Huang, Y. N., Yang, L. Y., Wang, J. Y., Lai, C. C., Chiu, C. T. and Wang, J. Y.* (2016). L-Ascorbate Protects Against Methamphetamine-Induced Neurotoxicity of Cortical Cells via Inhibiting Oxidative Stress, Autophagy, and Apoptosis. Mol Neurobiol. (Epub ahead of print)
   
2. Sung, C. W., Lee, H. C., Chiang, Y. H., Chiu, W. T., Chu, S. F., Ou, J. C., Tsai, S. H., Liao, K. H., Lin, C. M., Lin, J. W., Chen, G. S., Li, W. J. and Wang, J. Y.* (2016). Early dysautonomia detected by heart rate variability predicts late depression in female patients following mild traumatic brain injury. Psychophysiology 53(4): 455-464.
   
3. Chen, G. S., Liao, K. H., Bien, M. Y., Peng, G. S. and Wang, J. Y.* (2016). Increased Risk of Post-Trauma Stroke after Traumatic Brain Injury-Induced Acute Respiratory Distress Syndrome. J Neurotrauma. (Epub ahead of print)
   
4. Chiu, C. T., Wen, L. L., Pao, H. P., Yang, L. Y., Huang, Y. N. and Wang, J. Y.* (2015). Reparixin attenuates neuronal injury in experimental Klebsiella pneumoniae meningoencephalitis through dual effects on neuroprotection and neuroinflammation. Neuropathol Appl Neurobiol. (Epub ahead of print)
   
5. Huang, Y. N., Ho, Y. J., Lai, C. C., Chiu, C. T. and Wang, J. Y.* (2015). 1,25-Dihydroxyvitamin D3 attenuates endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures. J Neuroinflammation 12: 147.
   
6. Yang, L. Y., Chu, Y. H., Tweedie, D., Yu, Q. S., Pick, C. G., Hoffer, B. J., Greig, N. H. and Wang, J. Y.* (2015). Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury. Exp Neurol 269: 56-66.
   
7. Chen, G. S., Huang, K. F., Huang, C. C. and Wang, J. Y.* (2015). Thaliporphine derivative improves acute lung injury after traumatic brain injury. Biomed Res Int 2015: 729831. (Formerly titled Journal of Biomedicine and Biotechnology)
   
8. Sung, C. W., Chen, K. Y., Chiang, Y. H., Chiu, W. T., Ou, J. C., Lee, H. C., Tsai, S. H., Lin, J. W., Yang, C. M., Tsai, Y. R., Liao, K. H., Chen, G. S., Li, W. J. and Wang, J. Y.* (2016). Heart rate variability and serum level of insulin-like growth factor-1 are correlated with symptoms of emotional disorders in patients suffering a mild traumatic brain injury. Clin Neurophysiol 127(2): 1629-1638.
   
9. Liew, H. K., Kuo, J. S., Wang, J. Y.* and Pang, C. Y.* (2015). Granulocyte-Colony Stimulating Factor Increases Cerebral Blood Flow via a NO Surge Mediated by Akt/eNOS Pathway to Reduce Ischemic Injury. ScientificWorldJournal 2015: 657932.
   
10. Hsieh, T. H., Huang, Y. Z., Chen, J. J., Rotenberg, A., Chiang, Y. H., Chen W. S., Chang, V., Wang, J. Y.*, Peng, C. W.* (2015). Novel use of theta burst cortical electrical stimulation for modulating motor plasticity in rats. J Med Biol Eng (35):62-68.
    
11. Wang, H. W.*, Chao, P. Z., Lee, F. P. and Wang, J. Y.* (2015). Benzydamine oral spray inhibiting parasympathetic function of tracheal smooth muscle. Clin Exp Otorhinolaryngol 8(1): 65-68.
    
12. Chiu, C. T., Wen, L. L., Pao, H. P., Yang, L. Y., Huang, Y. N. and Wang, J. Y.* (2015). Reparixin attenuates neuronal injury in experimental Klebsiella pneumoniae meningoencephalitis through dual effects on neuroprotection and neuroinflammation. Neuropathol Appl Neurobiol.
    
13. Liu, K. H., Yang, S. T., Lin, Y. K., Lin, J. W., Lee, Y. H., Wang, J. Y., Hu, C. J., Lin, E. Y., Chen, S. M., Then, C. K. and Shen, S. C. (2015). Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis. Oncotarget 6(7): 5088-5101.
    
14. Baratz, R., Tweedie, D., Wang, J. Y., Rubovitch, V., Luo, W., Hoffer, B. J., Greig, N. H. and Pick, C. G. (2015). Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice. J Neuroinflammation 12: 45.
    
15. Liu, K. H., Yang, S. T., Lin, Y. K., Lin, J. W., Lee, Y. H., Wang, J. Y., Hu, C. J., Lin, E. Y., Chen, S. M., Then, C. K. and Shen, S. C. (2015). Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis. Oncotarget 6(7): 5088-5101.
    
16. Lu, K. T., Huang, T. C., Wang, J. Y., You, Y. S., Chou, J. L., Chan, M. W., Wo, P. Y., Amstislavskaya, T. G., Tikhonova, M. A. and Yang, Y. L. (2015). NKCC1 mediates traumatic brain injury-induced hippocampal neurogenesis through CREB phosphorylation and HIF-1alpha expression. Pflugers Arch 467(8): 1651-1661. (Epub ahead of print)
    
17. Wang, J. Y., Lee, C. T. and Wang, J. Y. (2014). Nitric oxide plays a dual role in the oxidative injury of cultured rat microglia but not astroglia. Neuroscience 281C: 164-177.
    
18. Huang, K. F., Hsu, W. C., Hsiao, J. K., Chen, G. S. and Wang, J. Y.* (2014). Collagen-glycosaminoglycan matrix implantation promotes angiogenesis following surgical brain trauma. Biomed Res Int 2014: 672409. (Formerly titled Journal of Biomedicine and Biotechnology)
    
19. Huang, Y. N., Lai, C. C., Chiu, C. T., Lin, J. J. and Wang, J. Y.* (2014). L-ascorbate attenuates the endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation and NF-kappaB translocation in cortical neurons/glia Cocultures. PLoS One 9(7): e97276.
    
20. Hsieh, T. H., Huang, Y. Z., Rotenberg, A., Pascual-Leone, A., Chiang, Y. H., Wang, J. Y. and Chen, J. J. (2015). Functional Dopaminergic Neurons in Substantia Nigra are Required for Transcranial Magnetic Stimulation-Induced Motor Plasticity. Cereb Cortex 25(7): 1806-1814. (Epub ahead of print).
    
21. Rachmany, L., Tweedie, D., Rubovitch, V., Yu, Q. S., Li, Y., Wang, J. Y., Pick, C. G. and Greig, N. H. (2013). Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α. PLoS One 8(11): e79837.
    
22. Tai, Y. T., Lee, W. Y., Lee, F. P., Lin, T. J., Shih, C. L., Wang, J. Y.*, Chiu, W. T. and Hung, K. S. (2014). Low dose of valproate improves motor function after traumatic brain injury. Biomed Res Int 2014: 980657. (Formerly titled Journal of Biomedicine and Biotechnology)
    
23. Chang, B. C., Liu, D. H., Chang, J. L., Lee, S. H. and Wang, J. Y.* (2014). Plantar pressure analysis of accommodative insole in older people with metatarsalgia. Gait Posture 39(1): 449-454.
    
24. Li, C. W., Lin, Y. F., Liu, T. T. and Wang, J. Y.* (2013). Heme oxygenase-1 aggravates heat stress-induced neuronal injury and decreases autophagy in cerebellar Purkinje cells of rats. Exp Biol Med (Maywood) 238(7): 744-754.
    
25. Huang, Y. N., Wang, J. Y., Lee, C. T., Lin, C. H., Lai, C. C. and Wang, J. Y.* (2012). L-ascorbate attenuates methamphetamine neurotoxicity through enhancing the induction of endogenous heme oxygenase-1. Toxicol Appl Pharmacol 265(2): 241-252.
    
26. Huang, K. F., Hsu, W. C., Chiu, W. T. and Wang, J. Y.* (2012). Functional improvement and neurogenesis after collagen-GAG matrix implantation into surgical brain trauma. Biomaterials 33(7): 2067-2075.
    
27. Chang, B. C., Wang, J. Y., Huang, B. S., Lin, H. Y. and Lee, W. C. (2012). Dynamic impression insole in rheumatoid foot with metatarsal pain. Clin Biomech (Bristol, Avon) 27(2): 196-201.
    
28. Liew, H. K., Pang, C. Y., Hsu, C. W., Wang, M. J., Li, T. Y., Peng, H. F., Kuo, J. S. and Wang, J. Y.* (2012). Systemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats. J Neuroinflammation 9: 13.
    
29. Liew, H. K., Hsu, C. W., Wang, M. J., Kuo, J. S., Li, T. Y., Peng, H. F., Wang, J. Y.* and Pang, C. Y.* (2012). Therapeutic benefit of urocortin in rats with intracerebral hemorrhage. J Neurosurg 116(1): 193-200.
    
30. Chiu, C. T., Wen, L. L., Pao, H. P. and Wang, J. Y.* (2011). Cortistatin is induced in brain tissue and exerts neuroprotection in a rat model of bacterial meningoencephalitis. J Infect Dis 204(10): 1563-1572.
    
31. Lui, C. C., Wang, J. Y., Tain, Y. L., Chen, Y. C., Chang, K. A., Lai, M. C. and Huang, L. T. (2011). Prenatal stress in rat causes long-term spatial memory deficit and hippocampus MRI abnormality: differential effects of postweaning enriched environment. Neurochem Int 58(3): 434-441.