James Shorter Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, USA
2 protocols

Emma Robinson Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 2019-2020
1 protocol

Lin Guo
  • Assistant Professor, Biochemistry and Molecular Biology, Thomas Jefferson University, 2019-
Research focus
  • -
  • 1 Author merit


PhD, University of Pennsylvania, United States, 2011


1 Protocol published
Karyopherin-β2 Inhibits and Reverses Aggregation and Liquid-liquid Phase Separation of the ALS/FTD-Associated Protein FUS
Authors:  Emma Robinson, James Shorter and Lin Guo, date: 08/20/2020, view: 1939, Q&A: 0
The study of RNA-binding proteins (RBP) offers insight into the mechanisms of pathologic protein aggregation in neurodegenerative diseases. We developed a protocol for purifying an RBP FUS and a nuclear import receptor (NIR) Kapβ2 and testing the ...
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