Vito G. D'Agostino
  • Group Leader, Department of Cellular, Computational and Integrative Biology, University of Trento, 2018-
Research focus
  • Cancer biology
  • 1 Author merit

Education

Ph.D. in genetics and Biomolecular Sciences, Department of Genetics and Microbiology, University of Pavia, Italy, 2010

Publications

Selected publications:
• Notarangelo, M., Zucal, C., Modelska, A., Pesce, I., Scarduelli, G., Potrich, C., Lunelli, L., Pederzolli, C., Pavan, P., la Marca, G., Pasini, L., Ulivi, P., Beltran, H., Demichelis, F., Provenzani, A., Quattrone, A. and D'Agostino, V. G. (2019). Ultrasensitive detection of cancer biomarkers by nickel-based isolation of polydisperse extracellular vesicles from blood. EBioMedicine 43: 114-126.
• D'Agostino, V. G., Sighel, D., Zucal, C., Bonomo, I., Micaelli, M., Lolli, G., Provenzani, A., Quattrone, A. and Adami, V. (2019). Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery. SLAS Discov 24(3): 314-331.
• Tebaldi, T., Zuccotti, P., Peroni, D., Köhn, M., Gasperini, L., Potrich, V., Bonazza, V., Dudnakova, T., Rossi, A., Sanguinetti, G., Conti, L., Macchi, P., D'Agostino, V., Viero, G., Tollervey, D., Huttelmaier, S. and Quattrone, A. (2018). HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA. Mol Cell 71(2): 256-270 e210.
• Dalle Vedove, A., Spiliotopoulos, D., D'Agostino, V. G., Marchand, J. R., Unzue, A., Nevado, C., Lolli, G. and Caflisch, A. (2018). Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains. ChemMedChem 13(14): 1479-1487.
• Manzoni, L., Zucal, C., Maio, D. D., D'Agostino, V. G., Thongon, N., Bonomo, I., Lal, P., Miceli, M., Baj, V., Brambilla, M., Cerofolini, L., Elezgarai, S., Biasini, E., Luchinat, C., Novellino, E., Fragai, M., Marinelli, L., Provenzani, A. and Seneci, P. (2018). Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors. J Med Chem 61(4): 1483-1498.
• Lal, P., Cerofolini, L., D'Agostino, V. G., Zucal, C., Fuccio, C., Bonomo, I., Dassi, E., Giuntini, S., Di Maio, D., Vishwakarma, V., Preet, R., Williams, S. N., Fairlamb, M. S., Munk, R., Lehrmann, E., Abdelmohsen, K., Elezgarai, S. R., Luchinat, C., Novellino, E., Quattrone, A., Biasini, E., Manzoni, L., Gorospe, M., Dixon, D. A., Seneci, P., Marinelli, L., Fragai, M. and Provenzani, A. (2017). Regulation of HuR structure and function by dihydrotanshinone-I. Nucleic Acids Res 45(16): 9514-9527.
• Mandrioli, J., Crippa, V., Cereda, C., Bonetto, V., Zucchi, E., Gessani, A., Ceroni, M., Chio, A., D'Amico, R., Monsurro, M. R., Riva, N., Sabatelli, M., Silani, V., Simone, I. L., Soraru, G., Provenzani, A., D'Agostino, V. G., Carra, S. and Poletti, A. (2019). Proteostasis and ALS: protocol for a phase II, randomised, double-blind, placebo-controlled, multicentre clinical trial for colchicine in ALS (Co-ALS). BMJ Open 9(5): e028486.
1 Protocol published
Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids
Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy ...
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