Ph.D. (Molecular Biology), University of Göttingen, International Max-Planck Research School, Germany, 2005
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Schiller, L. T., Lemus-Diaz, N., Rinaldi Ferreira, R., Böker, K. O. and Gruber, J. (2018). Enhanced Production of Exosome-Associated AAV by Overexpression of the Tetraspanin CD9. Molecular Therapy. Methods & Clinical Development 9: 278-287.
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Hoffmann, D. B., Gruber, J., Böker, K. O., Deppe, D., Sehmisch, S., Schilling, A. F., Lemus-Diaz, N., Komrakova, M. and Schneider, S. (2018). Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis. Molecular Therapy. Nucleic Acids 12: 443-452.
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Boker, K. O., Lemus-Diaz, N., Rinaldi Ferreira, R., Schiller, L., Schneider, S. and Gruber, J. (2018). The Impact of the CD9 Tetraspanin on Lentivirus Infectivity and Exosome Secretion. Mol Ther 26(2): 634-647.
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Zmora, P., Molau-Blazejewska, P., Bertram, S., Walendy-Gnirss, K., Nehlmeier, I., Hartleib, A., Moldenhauer, A. S., Konzok, S., Dehmel, S., Sewald, K., Brinkmann, C., Curths, C., Knauf, S., Gruber, J., Matz-Rensing, K., Dahlmann, F., Braun, A. and Pohlmann, S. (2017). Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin. PLoS One 12(5): e0176597.
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Pöhlmann, S., Krüger, A., Hafezi, W., Schneider, S., Gruber, J., Winkler, M., and Kaul, A. (2017). Detection systems for antibody responses against herpes B virus. Primate Biol(4): 9-16.
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Lemus-Diaz, N., Boker, K. O., Rodriguez-Polo, I., Mitter, M., Preis, J., Arlt, M. and Gruber, J. (2017). Dissecting miRNA gene repression on single cell level with an advanced fluorescent reporter system. Sci Rep 7: 45197.
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Jo, P., Azizian, A., Salendo, J., Kramer, F., Bernhardt, M., Wolff, H. A., Gruber, J., Grade, M., Beissbarth, T., Ghadimi, B. M. and Gaedcke, J. (2017). Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy. Int J Mol Sci 18(6).
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Hoffmann, D. B., Boker, K. O., Schneider, S., Eckermann-Felkl, E., Schuder, A., Komrakova, M., Sehmisch, S. and Gruber, J. (2016). In Vivo siRNA Delivery Using JC Virus-like Particles Decreases the Expression of RANKL in Rats. Mol Ther Nucleic Acids 5: e298.
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Azizian, A., Gruber, J., Ghadimi, B. M. and Gaedcke, J. (2016). MicroRNA in rectal cancer. World J Gastrointest Oncol 8(5): 416-426.
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Gruber, J., See Too, W. C., Wong, M. T., Lavie, A., McSorley, T. and Konrad, M. (2012). Balance of human choline kinase isoforms is critical for cell cycle regulation: implications for the development of choline kinase-targeted cancer therapy. Febs j 279(11): 1915-1928.
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Brameier, M., Herwig, A., Reinhardt, R., Walter, L. and Gruber, J. (2011). Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs. Nucleic Acids Res 39(2): 675-686.
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Liu, Y. P., Gruber, J., Haasnoot, J., Konstantinova, P. and Berkhout, B. (2009). RNAi-mediated inhibition of HIV-1 by targeting partially complementary viral sequences. Nucleic Acids Res 37(18): 6194-6204.
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Hossbach, M., Gruber, J., Osborn, M., Weber, K. and Tuschl, T. (2006). Gene silencing with siRNA duplexes composed of target-mRNA-complementary and partially palindromic or partially complementary single-stranded siRNAs. RNA Biol 3(2): 82-89.
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Gruber, J., Manninga, H., Tuschl, T., Osborn, M. and Weber, K. (2005). Specific RNAi mediated gene knockdown in zebrafish cell lines. RNA Biol 2(3): 101-105.
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Gruber, J. (2005). Functional gene analysis in cultured vertebrate cells using siRNA mediated gene silencing. Dissertation. University of Gottingen.
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Gruber, J., Lampe, T., Osborn, M. and Weber, K. (2005). RNAi of FACE1 protease results in growth inhibition of human cells expressing lamin A: implications for Hutchinson-Gilford progeria syndrome. J Cell Sci 118(Pt 4): 689-696.
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Gruber, J., Boese, G., Tuschl, T., Osborn, M. and Weber, K. (2004). RNA interference by osmotic lysis of pinosomes: liposome-independent transfection of siRNAs into mammalian cells. Biotechniques 37(1): 96-102.
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Gruber, J., Harborth, J., Schnabel, J., Weber, K. and Hatzfeld, M. (2002). The mitotic-spindle-associated protein astrin is essential for progression through mitosis. J Cell Sci 115(Pt 21): 4053-4059.