Mina Bissell Biological System and Engineering, Lawrence Berkeley National Laboratory, United States, United States,
1 protocol

Sun-Young Lee
  • Research scientist, Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, USA, USA,
Research focus
  • Cancer biology
  • Breast Cancer
    Extracellular Matrix Signaling and Tissue Architecture
  • 1 Author merit


Doctoral degree, University of California, Berkeley, 2007

Lab information

Mina J. Bissell's lab


1. Fuzer AM, Lee SY, Mott JD, and Cominetti MR (2017). [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture. Journal of Cellular Biochemistry, 118(9):2693-2699

2. Snijders AM, Lee SY, Hang B, Hao W, Bissell MJ, and Mao JH (2017). FAM83 family oncogenes are broadly involved in human cancers: an integrative multi-omics approach. Molecular Oncology, 11(2):167-179

3. Lee SY, Lee H, Kim ES, Park S, Lee J and Ahn B (2015). WRN translocation from nucleolus to nucleoplasm is regulated by SIRT1 and required for DNA repair and the development of chemoresistance. Mutation Research 774: 40-48.

4. Lee SY, Lee GR, Woo DH, Park NH, Cha HJ, Moon YH and Han IS (2013). Depletion of Aurora A leads to upregulation of FoxO1 to induce cell cycle arrest in hepatocellular carcinoma cells. Cell Cycle 12(1):67-75.

5. Lee SY*, Meier R*, Furuta S*, Lenburg ME, Kenny PA, Xu R and Bissell MJ (2012). FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice. J Clin Invest. 122(9):3211-3220. *co-first authors
1 Protocol published
A Functionally Robust Phenotypic Screen that Identifies Drug Resistance-associated Genes Using 3D Cell Culture
Authors:  Sun-Young Lee and Mina J. Bissell, date: 11/20/2018, view: 3779, Q&A: 0
Drug resistance is a major obstacle in cancer treatment: A case in point is the failure of cancer patients to respond to tyrosine kinase inhibitors (TKI) of EGFR, a receptor that is highly expressed in many cancers. Identification of the targets and ...
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