Reviewer
Mukesh Mahajan
  • Research associate, Case Western Reserve university
Research fields
  • Biochemistry, Biophysics, Cancer Biology, Cell Biology, Immunology
Personal information

Education

PhD, Nanyang Technological University, 2014

Lab information

https://sites.google.com/view/mahajan-research/home

Research focus

Protein Biochemistry, Peptides, Biophysics, Structural Biology, and NMR Spectroscopy.

Publications

https://scholar.google.com/citations?user=4sDjls8AAAAJ&hl=en
1. Mahajan M., Lu B., Bharambe N., Mandal A., Wang R., Boatz C. J., Van der Wel P., Buck M., Qi X., and Ramachandran R. NMR identification of a conserved Drp1 cardiolipin-binding motif indispensable for mitochondrial fission. (Accepted In PNAS).
2. Navaratna T., Atangcho L., Mahajan M., Subramanian V., Case M., Min A., Tresnak D., Thurber G. M. Directed Evolution Using Stabilized Bacterial Peptide Display. Journal of American Chemical Society, (2020), 142, 4, 1882-1894.
3. Mahajan M., Ravula T., Prade E., Anantharamaiah G. M. and Ramamoorthy A. Probing membrane enhanced protein-protein interactions in the minimal redox complex of Cytochrome-P450 and P450-reductase. Chem. Comm, 2019, 55 (41): 5777-5780.
4. Mahajan M., Prade E., Im S.C., Zhang M., Gentry K., Anantharamaiah G. M., Waskell L. and Ramamoorthy A. A Minimal Functional Complex of CYP450 and FBD of CYP450 Reductase in Nanodiscs. Angewandte Chemie, 2018, 57(28): 8458-8462.
5. Mahajan M., Chatterjee D., Bhuvaneswari K., Pillay S., Bhattacharjya S. NMR Structure and Localization of a Large Fragment of the SARS-CoV Fusion Protein: Implications in Viral Cell Fusion. BBA-Biomembranes. 2018, 1860(2): 407-415.
6. Ravula T., Barnaba C., Mahajan M., Anantharamiah G.M., Im S.C., Waskell L., Ramamoorthy A. The Membrane Environment Drives Cytochrome P450’s Spin Transition and its Interaction with Cytochrome b5. Chem. Commun. 2017, 53, 12798-12801.
7. Gentry K., Prade E., Barnaba C., Zhang M., Mahajan M., Im S.C., Anantharamaiah G. M., Nagao S., Waskell L. and Ramamoorthy A. (2017) Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b5 and Cytochrome c. Scientific Reports, 2017, 7: 7793.
8. Kumar A., Mahajan M., Awasthi B., Tandon A., Harioudh M., Shree S., Singh P., Shukla P., Ramachandran R., Mitra K., Bhattacharjya S. and Ghosh J. K. Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities. Scientific Reports, 2017, 7: 39925.
9. D’Souza A. Mahajan M. and Bhattacharjya S. Designed Multi-stranded Heme Binding beta-Sheet Peptides in Membrane. Chemical Sciences, 2016, 7, 2563-2571. (Edge article).
10. Mahajan M. and Bhattacharjya S. NMR structure and Localization of Fusion Peptides of SARS-CoV: Implications in Membrane Fusion. BBA-Biomembranes, 2015, 1848 (2): 721–730.
11. Mahajan M. and Bhattacharjya S. Designed Di-Heme Binding Helical Transmembrane Protein. ChemBioChem. 2014, 15 (9): 1257-1262. (Inside cover of journal).
12. Mahajan M. and Bhattacharjya S. β-Hairpin Peptides: Heme Binding, Catalysis, and Structure in Detergent Micelles. Angew. Chem. Int. Ed. 2013, 52: 6430–6434.
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