Dilip Kumar
  • Research associate, Singapore Immunology network
Research fields
  • Molecular biology
Personal information

Education

Ph.D, Ludwig Maximilians University of Munich, Germany, 2010

Lab information

Dr. Amit Singhal
http://www.sign.a-star.edu.sg

Research focus

Molecular biology, Immunology, Genome editing

Publications

Integrated in silico and 3D in vitro model of macrophage migration in response to physical and chemical factors in the tumor microenvironment
Sharon Wei Ling Lee, R J Seager, Felix Litvak, Fabian Spill, Je Lin Sieow, Penny Hweixian Leong, Dillip Kumar, Alrina Shin Min Tan, Siew Cheng Wong, Giulia Adriani, Muhammad Hamid Zaman, and Roger D Kamm
Integrative Biology, Volume 12, Issue 4, April 2020

c-Rel gain in B cells drives germinal center reactions and autoantibody production.
Kober-Hasslacher M, Oh-Strauß H, Kumar D, Soberón V, Diehl C, Lech M, Engleitner T, Katab E, Fernandez Saiz V, Piontek G, Li H, Menze B, Ziegenhain C, Enard W, Rad R, Böttcher JP, Anders HJ, Rudelius M, Schmidt-Supprian M.
J Clin Invest. 2020 Mar

Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation.
Kumar D, Lee B, Puan KJ, Lee W, Luis BS, Yusof N, Andiappan AK, Del Rosario R, Poschmann J, Kumar P, DeLibero G, Singhal A, Prabhakar S, De Yun W, Poidinger M, Rötzschke O.
Sci Rep. 2019 Oct

Histone acetylome-wide association study of tuberculosis
Ricardo C.H. del Rosario, Jeremie Poschmann, Pavanish Kumar, Catherine Y. Cheng, Seow Theng Ong, Hajira Shreen Hajan, Dilip Kumar, Mardiana Marzuki, Xiaohua Lu, Andrea Lee, Yanxia Tang, Cynthia Bin Eng Chee, Carey Lim, Bernett Lee, Josephine Lum, Francesca Zolezzi, Michael Poidinger, Olaf Rotzschke, Chiea Chuen Khor, Yee T. Wang, K. George Chandy, Gennaro De Libero, Amit Singhal, Shyam Prabhakar
BioRXiv (May 21, 2019. https://doi.org/10.1101/644112

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
Dilip Kumar1,*, Kia Joo Puan1,*, Anand Kumar Andiappan1,*, Bernett Lee1, Geertje H.A. Westerlaken2, Doreen Haase1, Rossella Melchiotti1, Zhuang Li1, Nurhashikin Yusof1, Josephine Lum1, Geraldine Koh1, Foo Shihui1, Joe Yeong1,15, Alexessander Couto Alves3, Juha Pekkanen4, Liang Dan Sun5, Astrid Irwanto6, Benjamin P. Fairfax7, Vivek Naranbhai7, John E. A. Common8, Mark Tang11, Chin Keh Chuang16,17, Marjo-Riitta Jarvelin3,12,13,14, Julian C. Knight9, Xuejun Zhang5, Fook Tim Chew18, Shyam Prabhakar6, Liu Jianjun6, Wang De Yun10, Francesca Zolezzi1, Michael Poidinger1, E. Birgitte Lane8, Linde Meyaard2* and Olaf Rötzschke1* (Genome Med. 2017 Feb 20;9(1):18.)

Systematic characterization of basophil anergy.
Puan KJ, Andiappan AK, Lee B, Kumar D, Lai TS, Yeo G, Bercin D, Starke M, Haase D, Lum J, Chew FT, Connolly J, Wong SC, Zolezzi F, Poidinger M, Wang Y, Rötzschke O.
Allergy. 2016 Jun 8. doi: 10.1111/all.12952. [Epub ahead of print]

Thioredoxin-dependent regulation of AIF-mediated DNA damage.
Shelar SB, Kaminska KK, Reddy SA, Kumar D, Tan CT, Yu VC, Lu J, Holmgren A, Hagen T, Chew EH.
Free Radic Biol Med. 2015 Oct;87:125-36. doi: 10.1016/j.freeradbiomed.2015.06.029. Epub 2015 Jun 25.

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils.
Andiappan AK, Melchiotti R, Poh TY, Nah M, Puan KJ, Vigano E, Haase D, Yusof N, San Luis B, Lum J, Kumar D, Foo S, Zhuang L, Vasudev A, Irwanto A, Lee B, Nardin A, Liu H, Zhang F, Connolly J, Liu J, Mortellaro A, Wang de Y, Poidinger M, Larbi A, Zolezzi F, Rotzschke O.
Nat Commun. 2015 Aug 10;6:7971. doi: 10.1038/ncomms8971.

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation, hyperactivation, cause inflammation and autoimmunity in aged mice.
Chu Y, Vahl JC, Kumar D, Heger K, Bertossi A, Wójtowicz E, Soberon V, Schenten D, Mack B, Reutelshöfer M, Beyaert R, Amann K, van Loo G, Schmidt-Supprian M. (BLOOD, Nov 2010 Epub ahead of print)

JNK MAP kinase pathway regulates constitutive transcription of CCL5 by human natural killer cells through SP1
Dilip Kumar, Judith Hosse, Christine von Toerne, Elfriede Noessner and Peter J. Nelson (Journal of Immunology, 2009 182: 1011-1020)
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