Gal Haimovich Molecular Genetics, Weizmann Institute of Science, Israel
76 protocols

Hong Lian Institute of Neuroscience, Zhejiang University School of Medicine, China
1 protocol

Joshua Titlow 2 protocols

Neelanjan Bose Emery Pharma
29 protocols

Reviewer
Karthik Krishnamurthy
  • Post-Doc, Thomas Jefferson University
Research focus
  • Neuroscience
  • Neurodegeneration, ALS, neuromuscular junction, synaptic dysfunction, microscopy, stress granules

Education

PhD, National Institute of Mental Health and Neurosciences (NIMHANS), India, 2012

Lab information

Dr Piera Pasinelli lab
http://www.jefferson.edu/university/farber_institute/weinberg_als_center.html

Publications

https://scholar.google.com/citations?user=rx8auDgAAAAJ&hl=en&authuser=2
Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
Authors
Xinmei Wen, Wenzhi Tan, Thomas Westergard, Karthik Krishnamurthy, Yingxiao Markandaiah S Shashirekha .,Shi, Shaoyu Lin, A Neil Shneider, John Monaghan, Udai B Pandey, P Pasinelli, Justin K Ichida, Davide Trotti
Publication date
2014/12/17
Journal
Neuron
Volume
84
Issue
6
Pages
1213-1225
Publisher
Cell Press

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity
Authors
J Gavin Daigle, Karthik Krishnamurthy, Nandini Ramesh, Ian Casci, John Monaghan, Kevin McAvoy, Earl W Godfrey, Dianne C Daniel, Edward M Johnson, Zachary Monahan, Frank Shewmaker, Piera Pasinelli, Udai Bhan Pandey
Publication date
2016/4/1
Journal
Acta neuropathologica
Volume
131
Issue
4
Pages
605-620
Publisher
Springer Berlin Heidelberg

AMPA induced Ca2+ influx in motor neurons occurs through voltage gated Ca2+ channel and Ca2+ permeable AMPA receptor
Authors
Dinesh C Joshi, Mahendra Singh, Karthik Krishnamurthy, Preeti G Joshi, Nanda B Joshi
Publication date
2011/11/1
Journal
Neurochemistry international
Volume
59
Issue
6
Pages
913-921
Publisher
Pergamon


Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha
Authors
Azadeh Kia, Kevin McAvoy, Karthik Krishnamurthy, Davide Trotti, Piera Pasinelli
Publication date
2018
Journal
Glia
Volume
23298
Issue
doi: 10.1002/glia.23298.
Pages
doi: 10.1002/glia.23298.
Publisher
Wiley


Depalmitoylation preferentially downregulates AMPA induced Ca2+ signaling and neurotoxicity in motor neurons
Authors
Karthik Krishnamurthy, Bhupesh Mehta, Mahendra Singh, Bhanu P Tewari, Preeti G Joshi, Nanda B Joshi
Publication date
2013/9/5
Journal
Brain research
Volume
1529
Pages
143-153
Publisher
Elsevier
7 Protocols reviewed
Partial Transection of Adult Rat Optic Nerve as a Model of Secondary Degeneration in the Central Nervous System
Authors:  Carole A Bartlett and Melinda Fitzgerald, date: 12/20/2018, view: 1416, Q&A: 0
Injury to the central nervous system is characterized by damage that spreads from the initial point of impact into the surrounding adjacent tissue, in a phenomenon referred to as secondary degeneration. The optic nerve can be used to effectively ...
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Enzymatic Synthesis and Fractionation of Fluorescent PolyU RNAs
The physical properties of viral-length polyuridine (PolyU) RNAs, which cannot base-pair and form secondary structures, are compared with those of normal-composition RNAs, composed of comparable numbers of each of A, U, G and C nucleobases. In this ...
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