HongLok Lung University of Hong Kong
59 protocols

Jyotiska Chaudhuri Buck Institute for Research on Aging
28 protocols

Lee-Hwa Tai Universite de Sherbrooke
20 protocols

Pascal Fossat Université de Bordeaux
5 protocols

Clara Lubeseder-Martellato
  • Group leader, Technical University of Munich
Research focus
  • Cancer biology
  • Pancreatic ductal adenocarcinoma, endocytosis, GTPases, Ras signaling
  • 1 Author merit

Lab information



Lubeseder-Martellato, Hidalgo-Sastre, Heid, Boos, Briel, Schmid, Siveke (2017). Oncogenic KRas-induced increase in fluid-phase endocytosis is dependent on N-WASP and is required for the formation of pancreatic preneoplastic lesions. EBioMedicine 15, 90-99

Lubeseder-Martellato C, Hidalgo-Sastre A, Hartmann C, Alexandrow K, Kamyabi-Moghaddam Z, Sipos B, Wirth M, Neff F, Reichert M, Heid I, Schneider G, Braren R, Schmid RM, Siveke JT (2016). Membranous CD24 drives the epithelial phenotype of pancreatic cancer. Oncotarget.

Heid I, Lubeseder-Martellato C (equally contributed), Sipos B, Mazur PK, Lesina M, Schmid RM, Siveke JT (2011) Early requirement of Rac1 in a mouse model of pancreatic cancer. Gastroenterology 141: 719-730, 730 e711-717

Naschberger E, Lubeseder-Martellato C (equally contributed), Meyer N, Gessner R, Kremmer E, Gessner A, Sturzl M (2006) Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis. Am J Pathol 169: 1088-1099

Lubeseder-Martellato C, Guenzi E, Jorg A, Topolt K, Naschberger E, Kremmer E, Zietz C, Tschachler E, Hutzler P, Schwemmle M, Matzen K, Grimm T, Ensoli B, Sturzl M (2002) Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am J Pathol 161: 1749-1759: 409-420

Guenzi E, Topolt K, Cornali E, Lubeseder-Martellato C (equally contributed), Jorg A, Matzen K, Zietz C, Kremmer E, Nappi F, Schwemmle M, Hohenadl C, Barillari G, Tschachler E, Monini P, Ensoli B, Sturzl M (2001) The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines. EMBO J 20: 5568-5577
1 Protocol published
Isolation, Culture and Differentiation of Primary Acinar Epithelial Explants from Adult Murine Pancreas
Author:  Clara Lubeseder-Martellato, date: 07/05/2013, view: 7873, Q&A: 0
The adult pancreas possesses an intrinsic developmental plasticity whereby acinar cells can convert into ductal structures under some pathological conditions. Acinar tissue can be isolated from murine pancreas and kept in three-dimensional collagen ...
5 Protocols reviewed
Assessment of Murine Retinal Function by Electroretinography
Authors:  Gillie Benchorin, Melissa A. Calton, Marielle O. Beaulieu and Douglas Vollrath, date: 04/05/2017, view: 7902, Q&A: 0
The electroretinogram (ERG) is a sensitive and noninvasive method for testing retinal function. In this protocol, we describe a method for performing ERGs in mice. Contact lenses on the mouse cornea measure the electrical response to a light ...
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Establishment of Patient-Derived Xenografts in Mice
Authors:  Dongkyoo Park, Dongsheng Wang, Guo Chen and Xingming Deng, date: 11/20/2016, view: 7914, Q&A: 0
Patient-derived xenograft (PDX) models for cancer research have recently attracted considerable attention in both the academy and industry (Hidalgo et al., 2014; Wilding and Bodmer, 2014). PDX models have been developed from different tumor ...
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