Emilie Battivelli Buck institute
5 protocols

Fei Xiao Stanford University
1 protocol

Ivan Zanoni Harvard Medical School
78 protocols

Jose Reyes-Darias Vircell S.L.
9 protocols

Editor
Emilie Besnard
  • Research scientist, BioAge Labs
Research focus
  • Cell biology
  • mTOR signaling
    HIV latency and transcription
    Cell biology, senescence and aging
  • 0 Author merit
4 Protocols reviewed
High-throughput Flow Cytometry Assay to Investigate TDP43 Splicing Function
Authors:  H. Broder Schmidt and Rajat Rohatgi, date: 04/20/2020, view: 939, Q&A: 0
Mutations in RNA-binding proteins (RBPs) such as TDP43 are associated with transcriptome-wide splicing defects and cause severe neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The impact ...
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Measuring Procaspase-8 and -10 Processing upon Apoptosis Induction
Authors:  Sabine Pietkiewicz, Clara Wolfe, Jörn H. Buchbinder and Inna N. Lavrik, date: 01/05/2017, view: 6263, Q&A: 0
Apoptosis or programmed cell death is important for multicellular organisms to keep cell homeostasis and for the clearance of mutated or infected cells. Apoptosis can be induced by intrinsic or extrinsic stimuli. The first event in extrinsic ...
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6 Protocols edited
TZA, a Sensitive Reporter Cell-based Assay to Accurately and Rapidly Quantify Inducible, Replication-competent Latent HIV-1 from Resting CD4+ T Cells
Authors:  Anwesha Sanyal, Vatsala S. Rangachar and Phalguni Gupta, date: 05/20/2019, view: 2872, Q&A: 1
The latent HIV-1 viral reservoir in resting CD4+ (rCD4+) T cells represents a major barrier to an HIV-1 cure. There is an ongoing effort to identify therapeutic approaches that will eliminate or reduce the size of this ...
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Lentiviral Knockdown of Transcription Factor STAT1 in Peromyscus leucopus to Assess Its Role in the Restriction of Tick-borne Flaviviruses
Authors:  Adaeze O. Izuogu and R. Travis Taylor, date: 12/05/2017, view: 5799, Q&A: 0
Cellular infection with tick-borne flaviviruses (TBFVs) results in activation of the interferon (IFN) signaling pathway and subsequent upregulation of numerous genes termed IFN stimulated genes (ISGs) (Schoggins et al., 2011). Many ISGs ...
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