Education

Ph.D. in Chemistry, Faculty of Science, Kyoto University, 1983

Current position

Unit Leader, Disease resistance crop research unit, GMO Center, National Institute of Agrobiological Sciences, Japan

Publications (since 2005)

1. Goto, S., Sasakura-Shimoda, F., Suetsugu, M., Selvaraj, M. G., Hayashi, N., Yamazaki, M., Ishitani, M., Shimono, M., Sugano, S., Matsushita, A., Tanabata, T. and Takatsuji, H. (2014). Development of disease-resistant rice by optimized expression of WRKY45. Plant Biotechnol J. (Epub ahead of print)
   
2. Xu, X., Hayashi, N., Wang, C. T., Fukuoka, S., Kawasaki, S., Takatsuji, H., Jiang, C. J. (2014).Rice blast resistance gene Pikahei-1(t), a member of a resistance gene cluster on chromosome 4, encodes a nucleotide-binding site and leucine-rich repeat protein. Mol Breed 34: 691-700.
   
3. Akagi, A., Fukushima, S., Okada, K., Jiang, C. J., Yoshida, R., Nakayama, A., Shimono, M., Sugano, S., Yamane, H. and Takatsuji, H. (2014). WRKY45-dependent priming of diterpenoid phytoalexin biosynthesis in rice and the role of cytokinin in triggering the reaction. Plant Mol Biol 86(1-2): 171-183.
   
4. Yokotani, N., Sato, Y., Tanabe, S., Chujo, T., Shimizu, T., Okada, K., Yamane, H., Shimono, M., Sugano, S., Takatsuji, H., Kaku, H., Minami, E. and Nishizawa, Y. (2013). WRKY76 is a rice transcriptional repressor playing opposite roles in blast disease resistance and cold stress tolerance. J Exp Bot 64(16): 5085-5097.
   
5. Ueno, Y., Yoshida, R., Kishi-Kaboshi, M., Matsushita, A., Jiang, C. J., Goto, S., Takahashi, A., Hirochika, H. and Takatsuji, H. (2013). MAP kinases phosphorylate rice WRKY45. Plant Signal Behav 8(6): e24510.
   
6. Nakayama, A., Fukushima, S., Goto, S., Matsushita, A., Shimono, M., Sugano, S., Jiang, C. J., Akagi, A., Yamazaki, M., Inoue, H. and Takatsuji, H. (2013). Genome-wide identification of WRKY45-regulated genes that mediate benzothiadiazole-induced defense responses in rice. BMC Plant Biol 13: 150.
   
7. Matsushita, A., Inoue, H., Goto, S., Nakayama, A., Sugano, S., Hayashi, N. and Takatsuji, H. (2013). Nuclear ubiquitin proteasome degradation affects WRKY45 function in the rice defense program. Plant J 73(2): 302-313.
   
8. Jiang, C. J., Shimono, M., Sugano, S., Kojima, M., Liu, X., Inoue, H., Sakakibara, H. and Takatsuji, H. (2013). Cytokinins act synergistically with salicylic acid to activate defense gene expression in rice. Mol Plant Microbe Interact 26(3): 287-296.
   
9. Inoue, H., Hayashi, N., Matsushita, A., Xinqiong, L., Nakayama, A., Sugano, S., Jiang, C. J. and Takatsuji, H. (2013). Blast resistance of CC-NB-LRR protein Pb1 is mediated by WRKY45 through protein-protein interaction. Proc Natl Acad Sci U S A 110(23): 9577-9582.
   
10. Sugano, S., Sugimoto, T., Takatsuji, H. and Jiang, C. J. (2013). Induction of resistance to Phytophthora sojaein soyabean (Glycine max) by salicylic acid and ethylene. Plant Pathol 62:1048-1056.
    
11. Yazawa, K., Jiang, C. J., Kojima, M., Sakakibara, H. and Takatsuji, H. (2012). Reduction of abscisic acid levels or inhibition of abscisic acid signaling in rice during the early phase of Magnaporthe oryzae infection decreases its susceptibility to the fungus. Physiol Mol Plant Pathol 78: 1-7.
    
12. Shimono, M., Koga, H., Akagi, A., Hayashi, N., Goto, S., Sawada, M., Kurihara, T., Matsushita, A., Sugano, S., Jiang, C. J., Kaku, H., Inoue, H. and Takatsuji, H. (2012). Rice WRKY45 plays important roles in fungal and bacterial disease resistance. Mol Plant Pathol 13(1): 83-94.
    
13. Fukushima, S., Yoshida, M. and Takatsuji, H. (2012). Role of linkers between zinc fingers in spacing recognition by plant TFIIIA-type zinc-finger proteins. J Amino Acids 2012: 848037.
    
14. Sakurai, T., Kondou, Y., Akiyama, K., Kurotani, A., Higuchi, M., Ichikawa, T., Kuroda, H., Kusano, M., Mori, M., Saitou, T., Sakakibara, H., Sugano, S., Suzuki, M., Takahashi, H., Takahashi, S., Takatsuji, H., Yokotani, N., Yoshizumi, T., Saito, K., Shinozaki, K., Oda, K., Hirochika, H. and Matsui, M. (2011). RiceFOX: a database of Arabidopsis mutant lines overexpressing rice full-length cDNA that contains a wide range of trait information to facilitate analysis of gene function. Plant Cell Physiol 52(2): 265-273.
    
15. Kotake, T., Aohara, T., Hirano, K., Sato, A., Kaneko, Y., Tsumuraya, Y., Takatsuji, H. and Kawasaki, S. (2011). Rice Brittle culm 6 encodes a dominant-negative form of CesA protein that perturbs cellulose synthesis in secondary cell walls. J Exp Bot 62(6): 2053-2062.
    
16. Dubouzet, J. G., Maeda, S., Sugano, S., Ohtake, M., Hayashi, N., Ichikawa, T., Kondou, Y., Kuroda, H., Horii, Y., Matsui, M., Oda, K., Hirochika, H., Takatsuji, H. and Mori, M. (2011). Screening for resistance against Pseudomonas syringae in rice-FOX Arabidopsis lines identified a putative receptor-like cytoplasmic kinase gene that confers resistance to major bacterial and fungal pathogens in Arabidopsis and rice. Plant Biotechnol J 9(4): 466-485.
    
17. Babu, R., Jiang, C. J., Xu, X., Kottapalli, K. R., Takatsuji, H., Miyao, A., Hirochika, H. and Kawasaki, S. (2011). Isolation, fine mapping and expression profiling of a lesion mimic genotype, spl(NF4050-8) that confers blast resistance in rice. Theor Appl Genet 122(4): 831-854.
    
18. Sugano, S., Jiang, C. J., Miyazawa, S., Masumoto, C., Yazawa, K., Hayashi, N., Shimono, M., Nakayama, A., Miyao, M. and Takatsuji, H. (2010). Role of OsNPR1 in rice defense program as revealed by genome-wide expression analysis. Plant Mol Biol 74(6): 549-562.
    
19. Kishi-Kaboshi, M., Okada, K., Kurimoto, L., Murakami, S., Umezawa, T., Shibuya, N., Yamane, H., Miyao, A., Takatsuji, H., Takahashi, A. and Hirochika, H. (2010). A rice fungal MAMP-responsive MAPK cascade regulates metabolic flow to antimicrobial metabolite synthesis. Plant J 63(4): 599-612.
    
20. Jiang, C. J., Shimono, M., Sugano, S., Kojima, M., Yazawa, K., Yoshida, R., Inoue, H., Hayashi, N., Sakakibara, H. and Takatsuji, H. (2010). Abscisic acid interacts antagonistically with salicylic acid signaling pathway in rice-Magnaporthe grisea interaction. Mol Plant Microbe Interact 23(6): 791-798.
    
21. Hirano, K., Kotake, T., Kamihara, K., Tsuna, K., Aohara, T., Kaneko, Y., Takatsuji, H., Tsumuraya, Y. and Kawasaki, S. (2010). Rice BRITTLE CULM 3 (BC3) encodes a classical dynamin OsDRP2B essential for proper secondary cell wall synthesis. Planta 232(1): 95-108.
    
22. Hayashi, N., Inoue, H., Kato, T., Funao, T., Shirota, M., Shimizu, T., Kanamori, H., Yamane, H., Hayano-Saito, Y., Matsumoto, T., Yano, M. and Takatsuji, H. (2010). Durable panicle blast-resistance gene Pb1 encodes an atypical CC-NBS-LRR protein and was generated by acquiring a promoter through local genome duplication. Plant J 64(3): 498-510.
    
23. Shibuya, K., Fukushima, S. and Takatsuji, H. (2009). RNA-directed DNA methylation induces transcriptional activation in plants. Proc Natl Acad Sci U S A 106(5): 1660-1665.
    
24. Kondou, Y., Higuchi, M., Takahashi, S., Sakurai, T., Ichikawa, T., Kuroda, H., Yoshizumi, T., Tsumoto, Y., Horii, Y., Kawashima, M., Hasegawa, Y., Kuriyama, T., Matsui, K., Kusano, M., Albinsky, D., Takahashi, H., Nakamura, Y., Suzuki, M., Sakakibara, H., Kojima, M., Akiyama, K., Kurotani, A., Seki, M., Fujita, M., Enju, A., Yokotani, N., Saitou, T., Ashidate, K., Fujimoto, N., Ishikawa, Y., Mori, Y., Nanba, R., Takata, K., Uno, K., Sugano, S., Natsuki, J., Dubouzet, J. G., Maeda, S., Ohtake, M., Mori, M., Oda, K., Takatsuji, H., Hirochika, H. and Matsui, M. (2009). Systematic approaches to using the FOX hunting system to identify useful rice genes. Plant J 57(5): 883-894.
    
25. Jiang, C. J., Shimono, M., Maeda, S., Inoue, H., Mori, M., Hasegawa, M., Sugano, S. and Takatsuji, H. (2009). Suppression of the rice fatty-acid desaturase gene OsSSI2 enhances resistance to blast and leaf blight diseases in rice. Mol Plant Microbe Interact 22(7): 820-829.
    
26. Aohara, T., Kotake, T., Kaneko, Y., Takatsuji, H., Tsumuraya, Y. and Kawasaki, S. (2009). Rice BRITTLE CULM 5 (BRITTLE NODE) is involved in secondary cell wall formation in the sclerenchyma tissue of nodes. Plant Cell Physiol 50(11): 1886-1897
    
27. Jiang, C.-J., Sugano, S. and Takatsuji, H. (2008). An ArabidopsisSUPERMAN-like gene, AtZFP12, Expressed at Shoot Organ Boundaries Suppresses cell Growth. Journal of Plant Biology 51(6): 413-417. .
    
28. Jiang, C. J., Aono, M., Tamaoki, M., Maeda, S., Sugano, S., Mori, M. and Takatsuji, H. (2008). SAZ, a new SUPERMAN-like protein, negatively regulates a subset of ABA-responsive genes in Arabidopsis. Mol Genet Genomics 279(2): 183-192.
    
29. Shimono, M., Sugano, S., Nakayama, A., Jiang, C. J., Ono, K., Toki, S. and Takatsuji, H. (2007). Rice WRKY45 plays a crucial role in benzothiadiazole-inducible blast resistance. Plant Cell 19(6): 2064-2076.
    
30. Kubo, K. and Takatsuji, H. (2007). Transgene-dependent incompatibility induced by introduction of the SK2:ZPT2-10 chimeric gene in petunia. Transgenic Res 16(1): 85-97.
    
31. Agarwal, P., Arora, R., Ray, S., Singh, A. K., Singh, V. P., Takatsuji, H., Kapoor, S. and Tyagi, A. K. (2007). Genome-wide identification of C2H2 zinc-finger gene family in rice and their phylogeny and expression analysis. Plant Mol Biol 65(4): 467-485.
    
32. Kapoor, S. and Takatsuji, H. (2006). Silencing of an anther-specific zinc-finger gene, MEZ1, causes aberrant meiosis and pollen abortion in petunia. Plant Mol Biol 61(3): 415-430.
    
33. Nakagawa, H., Jiang, C. J., Sakakibara, H., Kojima, M., Honda, I., Ajisaka, H., Nishijima, T., Koshioka, M., Homma, T., Mander, L. N. and Takatsuji, H. (2005). Overexpression of a petunia zinc-finger gene alters cytokinin metabolism and plant forms. Plant J 41(4): 512-523.
    
34. Kapoor, M., Baba, A., Kubo, K., Shibuya, K., Matsui, K., Tanaka, Y. and Takatsuji, H. (2005). Transgene-triggered, epigenetically regulated ectopic expression of a flower homeotic gene pMADS3 in Petunia. Plant J 43(5): 649-661.