Education

Ph.D. in Biophysics, Center of Biophys, Acad. Sci. of Armenia, 1981

D.Sc. (Doctor of Sciences, equivalent of the Research Professor title), Bogomolets Inst. Physiology, Acad. Sci. Ukraine, 1990

Current position

Research Professor and Project Director, Northport VAMC and Department of Neurobiology & Behavior, Stonybrook University, NY

Publications (selected)

1. Hunanyan, A. S., Petrosyan, H. A., Alessi, V. and Arvanian, V. L. (2013). Combination of Chondroitinase ABC and AAV-NT3 promotes neural plasticity at descending spinal pathways following thoracic contusion in rats. J Neurophysiol.
   
2. Petrosyan, H. A., Hunanyan, A. S., Alessi, V., Schnell, L., Levine, J. and Arvanian, V. L. (2013). Neutralization of inhibitory molecule NG2 improves synaptic transmission, retrograde transport, and locomotor function after spinal cord injury in adult rats. J Neurosci 33(9): 4032-4043.
   
3. Arvanian, V. (2013). Role of Neurotrophins in Spinal Plasticity and Locomotion. Current pharmaceutical design 19(24): 4509-4516.
   
4. Hunanyan, A. S., Petrosyan, H. A., Alessi, V. and Arvanian, V. L. (2012). Repetitive spinal electromagnetic stimulation opens a window of synaptic plasticity in damaged spinal cord: role of NMDA receptors. J Neurophysiol 107(11): 3027-3039.
   
5. Garcia-Alias, G., Petrosyan, H. A., Schnell, L., Horner, P. J., Bowers, W. J., Mendell, L. M., Fawcett, J. W. and Arvanian, V. L. (2011). Chondroitinase ABC combined with neurotrophin NT-3 secretion and NR2D expression promotes axonal plasticity and functional recovery in rats with lateral hemisection of the spinal cord. J Neurosci 31(49): 17788-17799.
   
6. Schnell, L., Hunanyan, A. S., Bowers, W. J., Horner, P. J., Federoff, H. J., Gullo, M., Schwab, M. E., Mendell, L. M. and Arvanian, V. L. (2011). Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. Eur J Neurosci 34(8): 1256-1267.
   
7. Hunanyan, A. S., Alessi, V., Patel, S., Pearse, D. D., Matthews, G. and Arvanian, V. L. (2011). Alterations of action potentials and the localization of Nav1.6 sodium channels in spared axons after hemisection injury of the spinal cord in adult rats. J Neurophysiol 105(3): 1033-1044.
   
8. Hunanyan, A. S., Garcia-Alias, G., Alessi, V., Levine, J. M., Fawcett, J. W., Mendell, L. M. and Arvanian, V. L. (2010). Role of chondroitin sulfate proteoglycans in axonal conduction in Mammalian spinal cord. J Neurosci 30(23): 7761-7769.
   
9. Shanthanelson, M., Arvanian, V. L. and Mendell, L. M. (2009). Input-specific plasticity of N-methyl-D-aspartate receptor-mediated synaptic responses in neonatal rat motoneurons. Eur J Neurosci 29(11): 2125-2136.
   
10. Arvanian, V. L., Schnell, L., Lou, L., Golshani, R., Hunanyan, A., Ghosh, A., Pearse, D. D., Robinson, J. K., Schwab, M. E., Fawcett, J. W. and Mendell, L. M. (2009). Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons. Exp Neurol 216(2): 471-480.
    
11. Arvanian, V. L., Manuzon, H., Davenport, M., Bushell, G., Mendell, L. M. and Robinson, J. K. (2006). Combined treatment with neurotrophin-3 and LSD facilitates behavioral recovery from double-hemisection spinal injury in neonatal rats. J Neurotrauma 23(1): 66-74.
    
12. Arvanian, V. L., Bowers, W. J., Anderson, A., Horner, P. J., Federoff, H. J. and Mendell, L. M. (2006). Combined delivery of neurotrophin-3 and NMDA receptors 2D subunit strengthens synaptic transmission in contused and staggered double hemisected spinal cord of neonatal rat. Exp Neurol 197(2): 347-352.
    
13. Aimone, J. B., Leasure, J. L., Perreau, V. M. and Thallmair, M. (2004). Spatial and temporal gene expression profiling of the contused rat spinal cord. Experimental neurology 189(2): 204-221.
    
14. Arvanian, V. L., Motin, V. and Mendell, L. M. (2005). Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord. J Pharmacol Exp Ther 312(2): 669-677.
    
15. Arvanian, V. L., Bowers, W. J., Petruska, J. C., Motin, V., Manuzon, H., Narrow, W. C., Federoff, H. J. and Mendell, L. M. (2004). Viral delivery of NR2D subunits reduces Mg²⁺ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. J Neurophysiol 92(4): 2394-2404.
    
16. Arvanian, V. L., Horner, P. J., Gage, F. H. and Mendell, L. M. (2003). Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat. J Neurosci 23(25): 8706-8712.
    
17. Mendell, L. M. and Arvanian, V. L. (2002). Diversity of neurotrophin action in the postnatal spinal cord. Brain Res Brain Res Rev 40(1-3): 230-239.
    
18. Arvanian, V. L. and Mendell, L. M. (2001). Acute modulation of synaptic transmission to motoneurons by BDNF in the neonatal rat spinal cord. Eur J Neurosci 14(11): 1800-1808.
    
19. Arvanian, V. L. and Mendell, L. M. (2001). Removal of NMDA receptor Mg(2+) block extends the action of NT-3 on synaptic transmission in neonatal rat motoneurons. J Neurophysiol 86(1): 123-129.
    
20. Mendell, L. M., Munson, J. B. and Arvanian, V. L. (2001). Neurotrophins and synaptic plasticity in the mammalian spinal cord. J Physiol 533(Pt 1): 91-97.
    
21. Arvanian, V., Seebach B.S. & Mendell, L. M. (2000). NT-3 evokes an LTP-like facilitation of AMPA/kainate receptor-mediated synaptic transmission in the neonatal rat spinal cord. J. Neurophysiol. 84(2): 752-8.
    
22. Seebach B.S., Arvanov V. & Mendell L.M. (1999). Effects of BDNF and NT-3 on development of Ia/motoneuron functional connectivity in neonatal rats. J. Neurophysiol 81(5):2398-405.