Steven Ziegler Immunology Program, Benaroya Research Institute, USA
1 protocol
Beatrice Li University of Oxford
7 protocols

Fanglian He Bio-protocol
205 protocols

Ivan Zanoni Harvard Medical School
78 protocols

Kate Hannan The Australian National University
15 protocols

Hongwei Han
  • Sanofi
Research focus
  • Immunology
  • 1 Author merit


Ph.D. in Immunology, Institute for Enzyme Research, University of Tokushima, Japan, 2007

Current position

Staff Scientist, Benaroya Research Institute

Affiliate Instructor, University of Washington


  1. Ziegler, S. F., Roan, F., Bell, B. D., Stoklasek, T. A., Kitajima, M. and Han, H. (2013). The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol 66: 129-155.
  2. Han, H., Headley, M. B., Xu, W., Comeau, M. R., Zhou, B. and Ziegler, S. F. (2013). Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages. J Immunol 190(3): 904-912.
  3. Han, H., Xu, W., Headley, M. B., Jessup, H. K., Lee, K. S., Omori, M., Comeau, M. R., Marshak-Rothstein, A. and Ziegler, S. F. (2012). Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma. Mucosal Immunol 5(3): 342-351.
  4. Roan, F.§, Bell, B. D.§, Stoklasek, T. A.§, Kitajima, M.§, Han, H.§ and Ziegler, S. F. (2012). The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond. J Leukoc Biol 91(6): 877-886. (§, co-1st author)
  5. Yano, M., Kuroda, N., Han, H., Meguro-Horike, M., Nishikawa, Y., Kiyonari, H., Maemura, K., Yanagawa, Y., Obata, K., Takahashi, S., Ikawa, T., Satoh, R., Kawamoto, H., Mouri, Y. and Matsumoto, M. (2008). Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance. J Exp Med 205(12): 2827-2838.
  6. Han, H. (2007). Target-organ specificity of autoimmunity is modified by thymic stroma and bone marrow-derived cells. J Med Invest 54(1-2): 54-64.
  7. Kinoshita, D., Hirota, F., Kaisho, T., Kasai, M., Izumi, K., Bando, Y., Mouri, Y., Matsushima, A., Niki, S., Han, H., Oshikawa, K., Kuroda, N., Maegawa, M., Irahara, M., Takeda, K., Akira, S. and Matsumoto, M. (2006). Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance. J Immunol 176(7): 3995-4002.
  8. Niki, S., Oshikawa, K., Mouri, Y., Hirota, F., Matsushima, A., Yano, M., Han, H., Bando, Y., Izumi, K., Matsumoto, M., Nakayama, K. I. and Kuroda, N. (2006). Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice. J Clin Invest 116(5): 1292-1301.
  9. Kuroda, N., Mitani, T., Takeda, N., Ishimaru, N., Arakaki, R., Hayashi, Y., Bando, Y., Izumi, K., Takahashi, T., Nomura, T., Sakaguchi, S., Ueno, T., Takahama, Y., Uchida, D., Sun, S., Kajiura, F., Mouri, Y., Han, H., Matsushima, A., Yamada, G. and Matsumoto, M. (2005). Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J Immunol 174(4): 1862-1870.
  10. Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J., Shimizu, N., Doucas, V., Nakayama, K. I., Kuroda, N. and Matsumoto, M. (2004). AIRE functions as an E3 ubiquitin ligase. J Exp Med 199(2): 167-172.
  11. Kajiura, F., Sun, S., Nomura, T., Izumi, K., Ueno, T., Bando, Y., Kuroda, N., Han, H., Li, Y., Matsushima, A., Takahama, Y., Sakaguchi, S., Mitani, T. and Matsumoto, M. (2004). NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. J Immunol 172(4): 2067-2075.
1 Protocol published
Bronchoalveolar Lavage and Lung Tissue Digestion
Authors:  Hongwei Han and Steven F. Ziegler, date: 08/20/2013, view: 30650, Q&A: 0
Bronchoalveolar lavage (BAL) is a simple but valuable and typically performed technique commonly used for studying the pathogenesis of lung diseases such as asthma and COPD. Cell counts can be combined with new methods for examining inflammatory ...
6 Protocols reviewed
Live Cell FRET Analysis of the Conformational Changes of Human P-glycoprotein
Authors:  Ryota Futamata, Noriyuki Kioka and Kazumitsu Ueda, date: 02/20/2021, view: 2346, Q&A: 0

The molecular mechanisms of P-glycoprotein (P-gp; also known as MDR1 or ABCB1) have been mainly investigated using artificial membranes such as lipid-detergent mixed micelles, artificial lipid bilayers, and membrane vesicles derived from cultured

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Generation and Testing of Fluorescent Adaptable Simple Theranostic (FAST) Proteins
This protocol provides a step-by-step method to create recombinant fluorescent fusion proteins that can be secreted from mammalian cell lines. This builds on many other recombinant protein and fluorescent protein techniques, but is among the first ...
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