Steven F. Ziegler
  • Immunology Program, Benaroya Research Institute, USA
Research focus
  • Immunology
  • 1 Author merit


Ph.D. in Molecular Biology, University of California, Los Angeles, 1984

Current position

Member and Director, Immunology Program, Benaroya Research Institute, Seattle, WA

Affiliate Professor, Department of Immunology, University of Washington, Seattle, WA

Publications (of 156 total)

  1. Han, H., Headley, M. B., Xu, W., Comeau, M. R., Zhou, B. and Ziegler, S. F. (2013). Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages. J Immunol 190(3): 904-912.
  2. Lee, H. C., Headley, M. B., Loo, Y. M., Berlin, A., Gale, M., Jr., Debley, J. S., Lukacs, N. W. and Ziegler, S. F. (2012). Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection. J Allergy Clin Immunol 130(5): 1187-1196 e1185.
  3. Ziegler, S. F. and Artis, D. (2010). Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol 11(4): 289-293.
  4. Larson, R. P., Zimmerli, S. C., Comeau, M. R., Itano, A., Omori, M., Iseki, M., Hauser, C. and Ziegler, S. F. (2010). Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses. J Immunol 184(6): 2974-2984.
  5. Headley, M. B., Zhou, B., Shih, W. X., Aye, T., Comeau, M. R. and Ziegler, S. F. (2009). TSLP conditions the lung immune environment for the generation of pathogenic innate and antigen-specific adaptive immune responses. J Immunol 182(3): 1641-1647.
  6. Lee, H. C., Headley, M. B., Iseki, M., Ikuta, K. and Ziegler, S. F. (2008). Cutting edge: Inhibition of NF-kappaB-mediated TSLP expression by retinoid X receptor. J Immunol 181(8): 5189-5193.
  7. Zhou, B., Headley, M. B., Aye, T., Tocker, J., Comeau, M. R. and Ziegler, S. F. (2008). Reversal of thymic stromal lymphopoietin-induced airway inflammation through inhibition of Th2 responses. J Immunol 181(9): 6557-6562.
  8. Omori, M. and Ziegler, S. (2007). Induction of IL-4 expression in CD4+ T cells by thymic stromal lymphopoietin. The Journal of Immunology 178(3): 1396-1404.
  9. Lee, H. C. and Ziegler, S. F. (2007). Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB. Proc Natl Acad Sci U S A 104(3): 914-919.
  10. Ziegler, S. F. and Liu, Y. J. (2006). Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat Immunol 7(7): 709-714.
  11. Zhou, B., Comeau, M. R., De Smedt, T., Liggitt, H. D., Dahl, M. E., Lewis, D. B., Gyarmati, D., Aye, T., Campbell, D. J. and Ziegler, S. F. (2005). Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat Immunol 6(10): 1047-1053.
  12. Yoo, J., Omori, M., Gyarmati, D., Zhou, B., Aye, T., Brewer, A., Comeau, M. R., Campbell, D. J. and Ziegler, S. F. (2005). Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med 202(4): 541-549.
  13. Carpino, N., Thierfelder, W. E., Chang, M. S., Saris, C., Turner, S. J., Ziegler, S. F. and Ihle, J. N. (2004). Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development. Mol Cell Biol 24(6): 2584-2592.
  14. Isaksen, D. E., Baumann, H., Zhou, B., Nivollet, S., Farr, A. G., Levin, S. D. and Ziegler, S. F. (2002). Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction. J Immunol 168(7): 3288-3294.
  15. Park, L. S., Martin, U., Garka, K., Gliniak, B., Di Santo, J. P., Muller, W., Largaespada, D. A., Copeland, N. G., Jenkins, N. A., Farr, A. G., Ziegler, S. F., Morrissey, P. J., Paxton, R. and Sims, J. E. (2000). Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor. J Exp Med 192(5): 659-670.
  16. Pandey, A., Ozaki, K., Baumann, H., Levin, S. D., Puel, A., Farr, A. G., Ziegler, S. F., Leonard, W. J. and Lodish, H. F. (2000). Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol 1(1): 59-64.
1 Protocol published
Bronchoalveolar Lavage and Lung Tissue Digestion
Authors:  Hongwei Han and Steven F. Ziegler, date: 08/20/2013, view: 30650, Q&A: 0
Bronchoalveolar lavage (BAL) is a simple but valuable and typically performed technique commonly used for studying the pathogenesis of lung diseases such as asthma and COPD. Cell counts can be combined with new methods for examining inflammatory ...
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