Education
PhD, Tohoku University, Japan, 2008
Current position
Assistant Professor, Department of Molecular Pharmacology, Tohoku University School of Medicine, Japan,
Publications
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Zhou, Y., Saito, M., Miyamoto, T., Novak, P., Shevchuk, A. I., Korchev, Y. E., Fukuma, T. and Takahashi, Y. (2018). Nanoscale Imaging of Primary Cilia with Scanning Ion Conductance Microscopy. Anal Chem 90(4): 2891-2895.
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Saito, M., Otsu, W., Hsu, K. S., Chuang, J. Z., Yanagisawa, T., Shieh, V., Kaitsuka, T., Wei, F. Y., Tomizawa, K. and Sung, C. H. (2017). Tctex-1 controls ciliary resorption by regulating branched actin polymerization and endocytosis. EMBO Rep 18(8): 1460-1472.
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Arashiki, N., Saito, M., Koshino, I., Kamata, K., Hale, J., Mohandas, N., Manno, S. and Takakuwa, Y. (2016). An Unrecognized Function of Cholesterol: Regulating the Mechanism Controlling Membrane Phospholipid Asymmetry. Biochemistry 55(25): 3504-3513.
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Yeh, C., Li, A., Chuang, J. Z., Saito, M., Caceres, A. and Sung, C. H. (2013). IGF-1 activates a cilium-localized noncanonical Gbetagamma signaling pathway that regulates cell-cycle progression. Dev Cell 26(4): 358-368.
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Goto, T., Chiba, A., Sukegawa, J., Yanagisawa, T., Saito, M. and Nakahata, N. (2013). Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G. Cell Signal 25(3): 690-697.
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Goto, S., Saito, M., Obara, Y., Moriya, T. and Nakahata, N. (2012). Involvement of lipid rafts in multiple signal transductions mediated by two isoforms of thromboxane A(2) receptor: dependency on receptor isoforms and downstream signaling types. Eur J Pharmacol 693(1-3): 15-24.
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Nusuetrong, P., Saito, M., Kikuchi, H., Oshima, Y., Moriya, T. and Nakahata, N. (2012). Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells. J Toxicol Sci 37(4): 803-812.
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Li, A., Saito, M., Chuang, J. Z., Tseng, Y. Y., Dedesma, C., Tomizawa, K., Kaitsuka, T. and Sung, C. H. (2011). Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors. Nat Cell Biol 13(4): 402-411.
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Conde, C., Arias, C., Robin, M., Li, A., Saito, M., Chuang, J. Z., Nairn, A. C., Sung, C. H. and Caceres, A. (2010). Evidence for the involvement of Lfc and Tctex-1 in axon formation. J Neurosci 30(19): 6793-6800.
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Saito, M., Tanaka, H., Sasaki, M., Kurose, H. and Nakahata, N. (2010). Involvement of aquaporin in thromboxane A2 receptor-mediated, G 12/13/RhoA/NHE-sensitive cell swelling in 1321N1 human astrocytoma cells. Cell Signal 22(1): 41-46.
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Uchiyama, K., Saito, M., Sasaki, M., Obara, Y., Higashiyama, S. and Nakahata, N. (2009). Thromboxane A2 receptor-mediated epidermal growth factor receptor transactivation: involvement of PKC-delta and PKC-epsilon in the shedding of epidermal growth factor receptor ligands. Eur J Pharm Sci 38(5): 504-511.
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Nasu, Y., Iwashita, M., Saito, M., Fushiya, S. and Nakahata, N. (2009). Inhibitory effects of Atractylodis lanceae rhizoma and Poria on collagen- or thromboxane A2-induced aggregation in rabbit platelets. Biol Pharm Bull 32(5): 856-860.
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Honma, S., Saito, M., Kikuchi, H., Saito, Y., Oshima, Y., Nakahata, N. and Yoshida, M. (2009). A reduction of epidermal growth factor receptor is involved in brefelamide-induced inhibition of phosphorylation of ERK in human astrocytoma cells. Eur J Pharmacol 616(1-3): 38-42.
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Saito, M., Shinohara, Y., Sasaki, H., Netsu, Y., Yoshida, M. and Nakahata, N. (2008). Type 1 angiotensin receptor (AT1-R)-mediated decrease in type 2 angiotensin receptor mRNA level is dependent on Gq and extracellular signal-regulated kinase 1//2 in AT1-R-transfected PC12 cells. J Neuroendocrinol 20(3): 299-308.
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Iwashita, M., Oka, N., Ohkubo, S., Saito, M. and Nakahata, N. (2007). Piperlongumine, a constituent of Piper longum L., inhibits rabbit platelet aggregation as a thromboxane A(2) receptor antagonist. Eur J Pharmacol 570(1-3): 38-42.
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Iwashita, M., Saito, M., Yamaguchi, Y., Takagaki, R. and Nakahata, N. (2007). Inhibitory effect of ethanol extract of Piper longum L. on rabbit platelet aggregation through antagonizing thromboxane A2 receptor. Biol Pharm Bull 30(7): 1221-1225.
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Saito, M., Hori, M., Obara, Y., Ohizumi, Y., Ohkubo, S. and Nakahata, N. (2006). Neurotrophic factor production in human astrocytoma cells by 2,5,6-tribromogramine via activation of epsilon isoform of protein kinase C. Eur J Pharm Sci 28(4): 263-271.
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Kikuchi, H., Saito, Y., Sekiya, J., Okano, Y., Saito, M., Nakahata, N., Kubohara, Y. and Oshima, Y. (2005). Isolation and synthesis of a new aromatic compound, brefelamide, from dictyostelium cellular slime molds and its inhibitory effect on the proliferation of astrocytoma cells. J Org Chem 70(22): 8854-8858.
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Saito, M., Sugai, M., Katsushima, Y., Yanagisawa, T., Sukegawa, J. and Nakahata, N. (2005). Increase in cell-surface localization of parathyroid hormone receptor by cytoskeletal protein 4.1G. Biochem J 392(Pt 1): 75-81.
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Sugai, M., Saito, M., Sukegawa, I., Katsushima, Y., Kinouchi, Y., Nakahata, N., Shimosegawa, T., Yanagisawa, T. and Sukegawa, J. (2003). PTH/PTH-related protein receptor interacts directly with Tctex-1 through its COOH terminus. Biochem Biophys Res Commun 311(1): 24-31.