Education

Ph.D. in Developmental Genetics, California Institute of Technology (Caltech), CA, USA, 1994

Current position

Director, Institute of Molecular Biology and Genetics, Seoul National University, South Korea (2012- present)
Professor, Department of Biophysics and Chemical Biology, Seoul National University, South Korea (2009- present)

Publications (representative)

1. Cho, S. W., Lee, J., Carroll, D., Kim, J. S. and Lee, J. (2013). Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins. Genetics 195(3): 1177-1180.
   
2. Lee, J. and Lee, J. (2013). Hypoxia-inducible Factor-1 (HIF-1)-independent hypoxia response of the small heat shock protein hsp-16.1 gene regulated by chromatin-remodeling factors in the nematode Caenorhabditis elegans. J Biol Chem 288(3): 1582-1589.
   
3. Lee, K., Shim, J., Bae, J., Kim, Y. J. and Lee, J. (2012). Stabilization of RNT-1 protein, runt-related transcription factor (RUNX) protein homolog of Caenorhabditis elegans, by oxidative stress through mitogen-activated protein kinase pathway. J Biol Chem 287(13): 10444-10452.
   
4. Lee, H., Choi, M. K., Lee, D., Kim, H. S., Hwang, H., Kim, H., Park, S., Paik, Y. K. and Lee, J. (2012). Nictation, a dispersal behavior of the nematode Caenorhabditis elegans, is regulated by IL2 neurons. Nat Neurosci 15(1): 107-112.
   
5. Kang, J., Bai, Z., Zegarek, M. H., Grant, B. D. and Lee, J. (2011). Essential roles of snap-29 in C. elegans. Dev Biol 355(1): 77-88.
   
6. Cho, S. C., Park, M. C., Keam, B., Choi, J. M., Cho, Y., Hyun, S., Park, S. C. and Lee, J. (2010). DDS, 4,4'-diaminodiphenylsulfone, extends organismic lifespan. Proc Natl Acad Sci U S A 107(45): 19326-19331.
   
7. Kang, J., Shin, D., Yu, J. R. and Lee, J. (2009). Lats kinase is involved in the intestinal apical membrane integrity in the nematode Caenorhabditis elegans. Development 136(16): 2705-2715.
   
8. Jo, H., Shim, J., Lee, J. H., Lee, J. and Kim, J. B. (2009). IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab 9(5): 440-448. (Co-corresponding author)
   
9. Nam, S., Min, K., Hwang, H., Lee, H. O., Lee, J. H., Yoon, J., Lee, H., Park, S. and Lee, J. (2009). Control of rapsyn stability by the CUL-3-containing E3 ligase complex. J Biol Chem 284(12): 8195-8206.
   
10. Joeng, K. S., Song, E. J., Lee, K. J. and Lee, J. (2004). Long lifespan in worms with long telomeric DNA. Nat Genet 36(6): 607-611.