Improve Research Reproducibility A Bio-protocol resource

AY
Reviewer
Ahmad Yatim
  • Post-Doc, St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, USA
Research fields
  • Cell Biology, Immunology
Personal information

Education

MD-PhD, University Paris-Est, 2016

Lab information

Jean-Laurent Casanova Lab
https://www.hgid.org/

Publications

https://orcid.org/0000-0002-4859-4085
Last-author (senior) original papers

• Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains.
Saidoune F, Lee D, Di Domizio J, Le Floc'h C, Jenelten R, Le Pen J, Bondet V, Joncic A, Morren MA, Béziat V, Zhang SY, Jouanguy E, Duffy D, Rice CM, Conrad C, Fellay J, Casanova JL, Gilliet M@, Yatim A@
J Exp Med. 2025 PMID: 40227192. (@ Corresponding authors).

First-author original papers

• Human LFA-1 governs T cell immune surveillance of the skin.
Yatim A@, Youssefian L, Idani A, Mourelatos H, Alipour N, Habibi L, Peel JN, Gaballa M, Kim C, Lee D, Le Floc’h C, Chan Y-H, Martin-Fernandez M, Pelletier L, Fayand A, Momenilandi M, Seeleuthner Y, Chaldebas M, Saeidian AH, Mahmoudi H, Nikbakht N, Deswarte C, Kerrouche N, Sahel H, Parvaneh N, Sherkat R, Chanal J, Firooz A, Alizadeh Z, Lorenzo-Diaz L, Mariaggi A-A, Ogishi M, Diep A, Hammadi B, Rinchai D, Lenormand C, Radosavljevic M, Rosain J, Zhang S-Y, Boisson B, Zhang P, Boisson-Dupuis S, Krueger JG, Prétet J-L, Waterboer T, Pourpak Z, Fazlollahi MR, Abel L, Bogunovic D, Shahrooei M, Cobat A, Carapito R, Molitor A, Vahidnezhad H, Béziat V, Bahram S, Jouanguy E@, Casanova J-L@
Science Immunol. 2026 (@Corresponding authors).

• The cGAS-STING pathway drives type I IFN immunopathology in COVID-19.
Di Domizio J*, Gulen M*, Saidoune F*, Thacker V*, Yatim A*, Sharma K, Nass T, Guenova E, Schaller M, Conrad C, Goepfert C, de Leval L, Garnier CV, Berezowska S, Dubois A, Gilliet M, Ablasser A.
Nature. 2022. (* Co-First authors).

• Paraneoplastic Pemphigus Revealed by Anti-Programmed Death-1 Pembrolizumab Therapy for Cutaneous Squamous Cell Carcinoma Complicating Hidradenitis Suppurative.
Yatim A, Bohelay G, Grootenboer-Mignot S, Prost-Squarcioni C, Alexandre M, Leroux C, Martin A, Maubec E, Caux F.
Frontiers in Medicine. 2019.

• NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.
Yatim A@, Benne C, Sobhian B, Laurent-Chabalier S, Deas O, Judde J, Lelievre JD, Levy Y, Benkirane M@.
Mol Cell. 2012. (@ Corresponding authors).

Co-author original papers

• Molecular profiling of inflammatory palmoplantar disorders for diagnosis and treatment optimization. Seremet T, Girardin A, Yatim A, Messina F, Jenelten R, Gottardo R, Conrad C, Di Domizio J, Gilliet M.
J Allergy Clin Immunol. 2026

• Immune modules to guide diagnosis and personalized treatment of inflammatory skin diseases. Seremet T, Di Domizio J, Girardin A, Yatim A, Jenelten R, Messina F, Saidoune F, Schlapbach C, Bogiatzi S, Minisini F, Garzorz-Stark N, Leuenberger M, Wüthrich H, Vernez M, Hohl D, Eyerich S, Eyerich K, Guenova E, Paul C, Gottardo R, Conrad C, Gilliet M.
Nat Commun. 2024 PMID: 39695162

• IL-7-dependent and -independent lineages of IL-7R-dependent human T cells. Arango-Franco CA, Ogishi M, Unger S, Delmonte OM, Orrego JC, Yatim A, Velasquez-Lopera MM, Zea-Vera AF, et al.
J Clin Invest. 2024. PMID: 39352394

• Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection. Arkin LM, Costa-da-Silva AC, Frere J, Ng A, Sharma R, Moon J, Bussan H, Kim CH, Javaid A, Steidl OR, Yatim A, et al.
iScience. 2024. PMID: 39156641

• Human TMEFF1 is a restriction factor for herpes simplex virus in the brain. Chan YH, Liu Z, Bastard P, Khobrekar N, Hutchison KM, Yamazaki Y, Fan Q, Matuozzo D, Harchnitz O, Kerrouche N, Nakajima K, Amin P, Yatim A, et al.
Nature. 2024. PMID: 39048830

• Human neutrophils drive skin autoinflammation by releasing interleukin (IL)-26. Baldo A, Di Domizio J, Yatim A, Vandenberghe-Dürr S, Jenelten R, Fries A, Grizzetti L, Kuonen F, Paul C, Modlin RL, Conrad C, Gilliet M.
J Exp Med. 2024

• FLT3LG governs the development of partially overlapping hematopoietic lineages in humans and mice. Momenilandi M, Lévy R, Sobrino S, Li J, Lagresle-Peyrou C, Esmaeilzadeh H, Fayand A, Le Floc'h C, Guérin A, Della Mina E, Shearer D, Delmonte OM, Yatim A, Mulder K, Mancini M, Rinchai D, Denis A, Neehus AL, Balogh K, et al.
Cell. 2024. PMID: 38701783

• Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals. Peel JN, Yang R, Le Voyer T, Gervais A, Rosain J, Bastard P, Behere A, Cederholm A, Bodansky A, Seeleuthner Y, Conil C, Ding JY, Lei WT, Bizien L, Soudee C, Migaud M, Ogishi M, Yatim A, Lee D, Bohlen J, Perpoint T, Perez L, et al.
J Clin Invest. 2024

• Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria. Bohlen J, Zhou Q, Philippot Q, Ogishi M, Rinchai D, Nieminen T, Seyedpour S, Parvaneh N, Rezaei N, Yazdanpanah N, Momenilandi M, Conil C, Neehus AL, Schmidt C, Arango-Franco CA, Voyer TL, Khan T, Yang R, Puchan J, Erazo L, Roiuk M, Vatovec T, Janda Z, Bagarić I, Materna M, Gervais A, Li H, Rosain J, Peel JN, Seeleuthner Y, Han JE, L'Honneur AS, Martin-Fernandez M, Horesh ME, Kochetkov T, Schmidt M, AlShehri MA, Salo E, Saxen H, ElGhazali G, Yatim A, et al.
Cell. 2023.

• It is not always chlorhexidine: Identification of benzoxonium chloride and lauramine oxide as culprit allergens in a popular antiseptic in Switzerland. Wüthrich H, Yatim A, Di Lucca J, Walker A, Ventejou S, Morren MA, Goossens A, Dendooven E, Aerts O, Gilliet M, Seremet T.
Contact Dermatitis. 2023.

• Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children. Lee D, Le Pen J*, Yatim A*, Dong B*, Aquino Y*, Ogishi M*, Pescarmona R, Talouarn E, Rinchai D, Zhang P, Perret M, Liu Z, Jordan I, Elmas Bozdemir S, Bayhan GI, Beaufils C, Bizien L, Bisiaux A, Lei W, Hasan M, Chen J, Gaughan C, et al.
Science. 2022. (* Co-Second authors).

• Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing. Laguette N, Brégnard C, Hue P, Basbous J, Yatim A, Larroque M, Kirchhoff F, Constantinou A, Sobhian B, Benkirane M.
Cell. 2014.

• Regulatory T Cells Negatively Affect IL-2 Production of Effector T Cells through CD39/Adenosine Pathway in HIV Infection
Jenabian MA, Seddiki N, Yatim A, Carriere M, Hulin A, Younas M, Ghadimi E, Kok A, Routy JP, Tremblay A, Sevigny J, Lelievre JD, Levy Y
PLOS Pathogens. 2013.

• SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells. Descours B, Cribier A, Bessia C, Ayinde D, Rice G, Crow Y, Yatim A, Schwartz O, Laguette N, Benkirane M.
Retrovirology. 2012.

• SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx. Laguette N, Sobhian B, Casartelli N, Ringeard M, Chable C, Ségéral E, Yatim A, Emiliani S, Schwartz O, Benkirane M.
Nature. 2011.

• HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK. Sobhian B, Laguette N, Yatim A, Nakamura M, Levy Y, Kiernan R, Benkirane M.
Mol Cell. 2010.

• Notch ligands potentiate IL-7-driven proliferation and survival of human thymocyte precursors. Magri M, Yatim A, Benne C, Balbo M, Henry A, Serraf A, Sakano S, Gazzolo L, Lévy Y, Lelièvre JD.
Eur J Immunol. 2009.

Review articles

• Skin manifestations of SARS-CoV-2 infection and its vaccination. Saidoune F, Yatim A, Di Domizio J, Gilliet M.
Curr Opin Immunol. 2025 PMID: 40939529

• The seven enigmas of SARS-CoV-2: from the past to the future. Andreakos E, Arkin L, Bastard P, Bolze A, Borghesi A, Brodin P, Casanova JL, Casari G, Cobat A, Drolet B, Fellay J, Hsieh E, Meyts I, Mogensen TH, Sancho-Shimizu V, Spaan AN, Su HC, Vinh DC, Yatim A, Zhang Q, Zhang SY; COVID Human Genetic Effort.
J Hum Immun. 2025 PMID: 41347066

• COVID-toes, a cutaneous sign of innate resistance to SARS-CoV-2. Yatim A, Gilliet M.
Rev Med Suisse. 2021.
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