TY  - JOUR
TI  - Morphological Evaluation of Wound Healing Events in the Excisional Wound Healing Model in Rats
AU  - Estevão , Ligia  Reis de Moura 
AU  - Cassini-Vieira, Puebla 
AU  - Leite, Ana Greice  Borba
AU  - Bulhões, Apolônia Agnes Vilar de Carvalho 
AU  - Barcelos, Lucíola da Silva
AU  - Evêncio-Neto, Joaquim 
VL  - 9
IS  - 13
PY  - 2019
DA  - 2019/07/05
SP  - e3285
C1  - Bio-protocol 2019;9:e3285
DO  - 10.21769/BioProtoc.3285
UR  - https://doi.org/10.21769/BioProtoc.3285
AB  - Skin wound healing is a complex process involving different events such as blood coagulation, inflammation, new blood vessels formation, and extracellular matrix deposition. These events can be observed by using histology techniques. However, the lack of the standardization of such parameters impacts on the reproducibility of results. Here, we describe a protocol to perform macroscopic and microscopic analyses of the events that occur during skin wound healing using the experimental model of excisional wounds in rats.
KW  - Rat excisional wound
KW  - Histological score
KW  - Angiogenesis
KW  - Inflammation
KW  - Collagen deposition
KW  - Epithelialization
JF  - Bio-protocol
SN  - 2331-8325
PB  - Bio-protocol LLC.
BIO101  - False