TY  - JOUR
TI  - IgE-mediated Chronic Allergic Inflammation (IgE-CAI)
AU  - Harada, Yasuyo  
AU  - Kubo, Masato  
VL  - 2
IS  - 19
PY  - 2012
DA  - 2012/10/05
SP  - e266
C1  - Bio-protocol 2012;2:e266
DO  - 10.21769/BioProtoc.266
UR  - https://doi.org/10.21769/BioProtoc.266
AB  - This system is one of a chronic allergic inflammation model. A single subcutaneous injection of antigens elicits a delayed-type response manifested by ear swelling. The entire response consists of three phases: Immediate, late, and chronic. The early-phase swelling peak within 1 h after allergen challenge is followed by the late-phase swelling 6-10 h late. Importantly, the ear swelling at the late-phase started on day2 and peak on day4. This late-phase ear swelling response is defined as IgE-mediated chronic allergic inflammation (IgE-CAI) and mainly regulated by basophils.
JF  - Bio-protocol
SN  - 2331-8325
PB  - Bio-protocol LLC.
BIO101  - False