Cell Biology

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    Protocols in Current Issue
    Electrophysiological Measurements of Isolated Blood Vessels
    Authors:  Samuel A Molina, Daniela Maier-Begandt, Brant E Isakson and Michael Koval, date: 03/20/2022, view: 696, Q&A: 0
    [Abstract]

    The lumen of blood vessels is covered by endothelial cells, which regulate their permeability to ions and solutes. Endothelial permeability depends on the vascular bed and cell phenotype, and is influenced by different disease states. Most characterization of endothelial permeability has been carried out using isolated cells in culture. While

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    Development of the Deoxycorticosterone Acetate (DOCA)-salt Hypertensive Rat Model
    Authors:  Nayara Pestana-Oliveira, David B. Nahey, Tim Johnson and John P. Collister, date: 08/05/2020, view: 3674, Q&A: 0
    [Abstract] According to the World Health Organization (WHO), nearly 1.13 billion people worldwide have hypertension, a major factor responsible for premature death globally. The inherent multifactorial nature of hypertension makes its study difficult since the chronic rise in blood pressure depends on the intricate connection between dietary, genetic ...
    Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)
    Authors:  Giulia Zanetti, Samuele Negro, Marco Pirazzini and Paola Caccin, date: 03/05/2018, view: 8019, Q&A: 0
    [Abstract] The neuromuscular junction (NMJ) is the specialized synapse by which peripheral motor neurons innervate muscle fibers and control skeletal muscle contraction. The NMJ is the target of several xenobiotics, including chemicals, plant, animal and bacterial toxins, as well as of autoantibodies raised against NMJ antigens. Depending on their ...
    Spinal Cord Preparation from Adult Red-eared Turtles for Electrophysiological Recordings during Motor Activity
    Authors:  Peter C Petersen and Rune W Berg , date: 07/05/2017, view: 10817, Q&A: 0
    [Abstract] Although it is known that the generation of movements is performed to a large extent in neuronal circuits located in the spinal cord, the involved mechanisms are still unclear. The turtle as a model system for investigating spinal motor activity has advantages, which far exceeds those of model systems using other animals. The high resistance to ...



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