Johannes Berger Department for Pathobiology of the Nervous System Center for Brain Reseach, Medical University of Vienna
1 protocol

Gerhard Zeitler Anorganic Chemistry University Vienna
1 protocol

Reviewer
Fabian Dorninger
  • Postdoctoral Researcher, Medical University of Vienna
Research focus
  • Neuroscience
  • ether lipids, phospholipids, neurotransmitter, peroxisome, metabolic disease, plasmalogen, synapse
  • 1 Author merit

Education

PhD, Medical University of Vienna, 2016

Publications

Dorninger F., Brodde A., Braverman N.E., Moser A.B., Just W.W., Forss-Petter S., Brügger B., Berger J.: Homeostasis of Phospholipids – The Level of Phosphatidylethanolamine Tightly Adapts to Changes in Ethanolamine Plasmalogens; BBA Mol Cell Biol Lipids, Feb 2015;1851(2):117-28. doi: 10.1016/j.bbalip.2014.11.005
Dorninger F., Wiesinger C., Braverman N., Forss-Petter S., Berger J.: Ether Lipid Deficiency Does Not Cause Neutropenia or Leukopenia in Mice and Men; Cell Metab, 2015 May 5;21(5):650-1. doi: 10.1016/j.cmet.2015.04.014.
Berger J., Dorninger F., Forss-Petter S., Kunze M.: Peroxisomes in brain development and function; BBA Mol Cell Res, 2016 May;1863(5):934-55. doi: 10.1016/j.bbamcr.2015.12.005
Dorninger F., Herbst R., Kravic B., Camurdanoglu B.Z., Macinkovic I., Zeitler G., Forss-Petter S., Strack S., Khan M.M., Waterham H.R., Rudolf R., Hashemolhosseini S., Berger J.: Reduced Muscle Strength in Ether Lipid-Deficient Mice Is Accompanied by Altered Development and Function of the Neuromuscular Junction; J Neurochem, 2017 Dec;143(5):569-583, doi: 10.1111/jnc.14082
Dorninger F., Forss-Petter S., Berger J.: From Peroxisomal Disorders to Common Neurodegenerative Diseases: The Role of Ether Phospholipids in the Nervous System; FEBS Lett, Sep 2017;591(18):2761-2788, doi: 10.1002/1873-3468.12788
Dorninger F., Moser A.B., Kou J., Wiesinger C., Forss-Petter S., Gleiss A., Hinterberger M., Jungwirth S., Fischer P., Berger J.: Alterations in the plasma levels of specific choline phospholipids in Alzheimer’s disease mimic accelerated aging; J Alzheimers Dis, 2018 Feb, 62(2):841-854, doi: 10.3233/JAD-171036
Trigueros-Motos L., van Capelleveen J.C., Torta F., Castaño D., Zhang L., Chai C., Kang M., Dimova L.G., Tietjen I., Radomski C., Tan L.J., Hwee T.C., Narayanaswamy P., Wu D., Dorninger F., Krishna Yakala G., Barhdadi A., Angeli V., Dubé M.-P., Berger J., Dallinga-Thie G.M., Tietge U.J.F., Wenk M.R., Hayden M.R., Kees Hovingh G., Singaraja R.R.: ABCA8 influences cholesterol efflux and can modulate high density lipoprotein cholesterol levels in humans; Arterioscler Thromb Vasc Biol, 2017 Nov;37(11):2147-2155, doi: 10.1161/ATVBAHA.117.309574
Honsho M., Dorninger F., Abe Y., Ohgi R., Berger J., Fujiki Y.: Impaired plasmalogen synthesis dysregulates liver X receptor-dependent transcription in cerebellum; J Biochem, 2019 Oct;166(4):353-361, doi: 10.1093/jb/mvz043
Dorninger F., König T., Scholze P., Berger M.L., Zeitler G., Wiesinger C., Gundacker A., Pollak D.D., Huck S., Just W.W., Forss-Petter S., Pifl C., Berger J.: Disturbed neurotransmitter homeostasis in ether lipid deficiency; Hum Mol Genet, 2019 Jun 15;28(12):2046-2061, doi: 10.1093/hmg/ddz040
Dorninger F., Gundacker A., Zeitler G., Pollak D.D., Berger J.: Ether lipid deficiency in mice produces a complex behavioral phenotype mimicking aspects of human psychiatric disorders; Int J Mol Sci, 2019, 20(16), 3929, doi: 10.3390/ijms20163929
Todt H., Dorninger F., Rothauer P.J., Schranz M., Fischer C.M., Luechtenborg C., Bruegger B., Gawali V.S., Berger J.: Oral batyl alcohol supplementation rescues decreased cardiac conduction in ether phospholipid-deficient mice; J Inherit Metab Dis, 2020 Sep;43(5):1046-1055; doi: 10.1002/jimd.12264
Dorninger F., Forss-Petter S., Wimmer I., Berger J.: Plasmalogens, platelet-activating factor and beyond - Ether lipids in signaling and neurodegeneration; Neurobiol Dis, 2020 Aug 27; 105061. doi: 10.1016/j.nbd.2020.105061
Dorninger F., Zeitler G., Berger J.: Nestlet shredding and nest building tests to assess features of psychiatric disorders in mice; Bio Prot
1 Protocol published
巢破坏和筑巢测试评估小鼠精神障碍的特征
Authors:  Fabian Dorninger, Gerhard Zeitler and Johannes Berger, date: 12/20/2020, view: 1367, Q&A: 0

Mimicking the various facets of human psychiatric and neurodevelopmental disorders in animal models is a challenging task. Nevertheless, mice have emerged as a widely used model system to study pathophysiology and treatment strategies for these

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