Research Assistant, Neuroscience, Curtin Health Innovation Research Institute, Sarich Neuroscience Research Institute, 8 Verdun St, Nedlands, 6009 WA, Australia, Australia
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Mao Y, Black
AMB, Milbourn HR, Krakonja S, Nesbit M, Bartlett CA, Fehily B, Takechi R, Yates
NJ, Fitzgerald M. The
Effects of a Combination of Ion Channel Inhibitors in Female Rats Following Repeated
Mild Traumatic Brain Injury. Int J Mol Sci. 2018 Oct
31;19(11). pii: E3408. doi: 10.3390/ijms19113408. PubMed PMID: 30384417.
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Toomey LM,
Bartlett CA, Majimbi M, Gopalasingam G, Rodger J, Fitzgerald M. Comparison of ion channel inhibitor combinations for
limiting secondary degeneration following partial optic nerve transection. Exp Brain Res. 2018 Oct 26. doi: 10.1007/s00221-018-5414-0. [Epub ahead of
print] PubMed PMID: 30367192.
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Giacci MK,
Bartlett CA, Smith NM, Iyer KS, Toomey LM, Jiang H, Guagliardo P, Kilburn MR,
Fitzgerald M. Oligodendroglia
Are Particularly Vulnerable to Oxidative Damage after Neurotrauma In Vivo. J Neurosci. 2018 Jul 18;38(29):6491-6504. doi: 10.1523/JNEUROSCI.1898-17.2018.
Epub 2018 Jun 18. PubMed PMID: 29915135.
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Smith NM,
Giacci MK, Gough A, Bailey C, McGonigle T, Black AMB, Clarke TO, Bartlett CA,
Swaminathan Iyer K, Dunlop SA, Fitzgerald M. Inflammation
and blood-brain barrier breach remote from the primary injury following
neurotrauma. J Neuroinflammation. 2018 Jul 7;15(1):201.
doi: 10.1186/s12974-018-1227-0. PubMed PMID: 29981582; PubMed Central PMCID:
PMC6035802.
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Chiha W,
LeVaillant CJ, Bartlett CA, Hewitt AW, Melton PE, Fitzgerald M, Harvey AR. Retinal genes are differentially expressed in areas of
primary versus secondary degeneration following partial optic nerve injury. PLoS One. 2018 Feb 9;13(2):e0192348. doi: 10.1371/journal.pone.0192348.
eCollection 2018. PubMed PMID: 29425209; PubMed Central PMCID: PMC5806857.
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O'Hare Doig
RL, Chiha W, Giacci MK, Yates NJ, Bartlett CA, Smith NM, Hodgetts SI, Harvey
AR, Fitzgerald M. Specific
ion channels contribute to key elements of pathology during secondary
degeneration following neurotrauma. BMC Neurosci. 2017
Aug 14;18(1):62. doi: 10.1186/s12868-017-0380-1. PubMed PMID: 28806920; PubMed
Central PMCID: PMC5557315.
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Yates NJ,
Lydiard S, Fehily B, Weir G, Chin A, Bartlett CA, Alderson J, Fitzgerald M. Repeated mild traumatic brain injury in female rats
increases lipid peroxidation in neurons. Exp Brain Res.
2017 Jul;235(7):2133-2149. doi: 10.1007/s00221-017-4958-8. Epub 2017 Apr 17.
PubMed PMID: 28417146.
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Yates NJ,
Giacci MK, O'Hare Doig RL, Chiha W, Ashworth BE, Kenna J, Bartlett CA,
Fitzgerald M. Delayed
treatment of secondary degeneration following acute optic nerve transection
using a combination of ion channel inhibitors. Neural
Regen Res. 2017 Feb;12(2):307-316. doi: 10.4103/1673-5374.200814. PubMed PMID:
28400815; PubMed Central PMCID: PMC5361517.
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O'Hare Doig
RL, Bartlett CA, Smith NM, Hodgetts SI, Dunlop SA, Hool L, Fitzgerald M. Specific combinations of ion channel inhibitors reduce
excessive Ca2+ influx as a consequence of oxidative stress and increase
neuronal and glial cell viability in vitro. Neuroscience.
2016 Dec 17;339:450-462. doi: 10.1016/j.neuroscience.2016.10.005. Epub 2016 Oct
8. PubMed PMID: 27725216.
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Lozić I,
Hartz RV, Bartlett CA, Shaw JA, Archer M, Naidu PSR, Smith NM, Dunlop SA, Iyer
KS, Kilburn MR, Fitzgerald M. Characterization
of polymeric nanoparticles for treatment of partial injury to the central
nervous system. Data Brief. 2016 Feb 16;7:152-156. doi:
10.1016/j.dib.2016.02.019. eCollection 2016 Jun. PubMed PMID: 28795116; PubMed
Central PMCID: PMC5540673.
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Ashworth BE,
Stephens E, Bartlett CA, Serghiou S, Giacci MK, Williams A, Hart NS, Fitzgerald
M. Comparative
assessment of phototherapy protocols for reduction of oxidative stress in
partially transected spinal cord slices undergoing secondary degeneration. BMC Neurosci. 2016 May 18;17(1):21. doi: 10.1186/s12868-016-0259-6. PubMed
PMID: 27194427; PubMed Central PMCID: PMC4872332.
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Smith NM,
Gachulincova I, Ho D, Bailey C, Bartlett CA, Norret M, Murphy J, Buckley A,
Rigby PJ, House MJ, St Pierre T, Fitzgerald M, Iyer KS, Dunlop SA. An Unexpected Transient Breakdown of the Blood Brain
Barrier Triggers Passage of Large Intravenously Administered Nanoparticles. Sci Rep. 2016 Mar 4;6:22595. doi: 10.1038/srep22595. PubMed PMID: 26940762;
PubMed Central PMCID: PMC4778073.
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Lozić I,
Hartz RV, Bartlett CA, Shaw JA, Archer M, Naidu PS, Smith NM, Dunlop SA, Iyer
KS, Kilburn MR, Fitzgerald M. Enabling
dual cellular destinations of polymeric nanoparticles for treatment following
partial injury to the central nervous system. Biomaterials. 2016 Jan;74:200-16. doi: 10.1016/j.biomaterials.2015.10.001. Epub
2015 Oct 9. PubMed PMID: 26461115.
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O'Hare Doig
RL, Bartlett CA, Maghzal GJ, Lam M, Archer M, Stocker R, Fitzgerald M. Reactive species and oxidative stress in optic nerve
vulnerable to secondary degeneration. Exp Neurol. 2014
Nov;261:136-46. doi: 10.1016/j.expneurol.2014.06.007. Epub 2014 Jun 12. PubMed
PMID: 24931225.
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Giacci MK,
Wheeler L, Lovett S, Dishington E, Majda B, Bartlett CA, Thornton E,
Harford-Wright E, Leonard A, Vink R, Harvey AR, Provis J, Dunlop SA, Hart NS,
Hodgetts S, Natoli R, Van Den Heuvel C, Fitzgerald M. Differential effects of 670 and 830 nm red near infrared
irradiation therapy: a comparative study of optic nerve injury, retinal degeneration,
traumatic brain and spinal cord injury. PLoS One. 2014
Aug 8;9(8):e104565. doi: 10.1371/journal.pone.0104565. eCollection 2014. PubMed
PMID: 25105800; PubMed Central PMCID: PMC4126771.
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Lozić I,
Bartlett CA, Shaw JA, Iyer KS, Dunlop SA, Kilburn MR, Fitzgerald M. Changes in subtypes of Ca microdomains following partial
injury to the central nervous system. Metallomics. 2014
Mar;6(3):455-64. doi: 10.1039/c3mt00336a. Epub 2014 Jan 3. PubMed PMID:
24425149.
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Savigni DL,
O'Hare Doig RL, Szymanski CR, Bartlett CA, Lozić I, Smith NM, Fitzgerald M. Three Ca2+ channel inhibitors in combination limit
chronic secondary degeneration following neurotrauma. Neuropharmacology. 2013 Dec;75:380-90. doi: 10.1016/j.neuropharm.2013.07.034.
Epub 2013 Aug 16. PubMed PMID: 23958451.
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Cummins N,
Bartlett CA, Archer M, Bartlett E, Hemmi JM, Harvey AR, Dunlop SA, Fitzgerald
M. Changes
to mitochondrial ultrastructure in optic nerve vulnerable to secondary
degeneration in vivo are limited by irradiation at 670 nm. BMC Neurosci. 2013 Sep 8;14:98. doi: 10.1186/1471-2202-14-98. PubMed PMID:
24011177; PubMed Central PMCID: PMC3844486.
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Szymanski
CR, Chiha W, Morellini N, Cummins N, Bartlett CA, O'Hare Doig RL, Savigni DL,
Payne SC, Harvey AR, Dunlop SA, Fitzgerald M. Paranode
Abnormalities and Oxidative Stress in Optic Nerve Vulnerable to Secondary
Degeneration: Modulation by 670 nm Light Treatment. PLoS
One. 2013 Jun 19;8(6):e66448. doi: 10.1371/journal.pone.0066448. Print 2013.
PubMed PMID: 23840470; PubMed Central PMCID: PMC3686728.
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Payne SC,
Bartlett CA, Savigni DL, Harvey AR, Dunlop SA, Fitzgerald M. Early proliferation does not prevent the loss of
oligodendrocyte progenitor cells during the chronic phase of secondary degeneration
in a CNS white matter tract. PLoS One. 2013 Jun
11;8(6):e65710. doi: 10.1371/journal.pone.0065710. Print 2013. PubMed PMID:
23776532; PubMed Central PMCID: PMC3679191.
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Payne SC,
Bartlett CA, Harvey AR, Dunlop SA, Fitzgerald M. Myelin
sheath decompaction, axon swelling, and functional loss during chronic
secondary degeneration in rat optic nerve. Invest
Ophthalmol Vis Sci. 2012 Sep 4;53(10):6093-101. doi: 10.1167/iovs.12-10080.
PubMed PMID: 22879411.
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Harrison J,
Bartlett CA, Cowin G, Nicholls PK, Evans CW, Clemons TD, Zdyrko B, Luzinov IA,
Harvey AR, Iyer KS, Dunlop SA, Fitzgerald M. In
vivo imaging and biodistribution of multimodal polymeric nanoparticles
delivered to the optic nerve. Small. 2012 May
21;8(10):1579-89. doi: 10.1002/smll.201102648. Epub 2012 Mar 13. PubMed PMID:
22411702.
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Wells J,
Kilburn MR, Shaw JA, Bartlett CA, Harvey AR, Dunlop SA, Fitzgerald M. Early in vivo changes in calcium ions,oxidative stress
markers, and ion channel immunoreactivity following partial injury to the optic
nerve. J Neurosci Res. 2012 Mar;90(3):606-18. doi:
10.1002/jnr.22784. Epub 2011 Oct 31. PubMed PMID: 22038561.
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Payne SC,
Bartlett CA, Harvey AR, Dunlop SA, Fitzgerald M. Chronic
swelling and abnormal myelination during secondary degeneration after partial
injury to a central nervous system tract. J Neurotrauma.
2011 Jun;28(6):1077-88. doi: 10.1089/neu.2010.1665. Epub 2011 May 5. PubMed
PMID: 21381867.
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Ho D,
Fitzgerald M, Bartlett CA, Zdyrko B, Luzinov IA, Dunlop SA, Swaminathan Iyer K. The
effects of concentration-dependent morphology of self-assembling RADA16
nanoscaffolds on mixed retinal cultures. Nanoscale. 2011
Mar;3(3):907-10. doi: 10.1039/c0nr00666a. Epub 2010 Dec 3. PubMed PMID:
21132164.
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Fitzgerald
M, Bartlett CA, Payne SC, Hart NS, Rodger J, Harvey AR, Dunlop SA. Near infrared light reduces oxidative stress and
preserves function in CNS tissue vulnerable to secondary degeneration following
partial transection of the optic nerve. J Neurotrauma.
2010 Nov;27(11):2107-19. doi: 10.1089/neu.2010.1426. PubMed PMID: 20822460.
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Selt M,
Bartlett CA, Harvey AR, Dunlop SA, Fitzgerald M. Limited
restoration of visual function after partial optic nerve injury; a time course
study using the calcium channel blocker lomerizine. Brain
Res Bull. 2010 Mar 16;81(4-5):467-71. doi: 10.1016/j.brainresbull.2009.11.004.
Epub 2009 Nov 11. PubMed PMID: 19913075.
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Fitzgerald
M, Bartlett CA, Harvey AR, Dunlop SA. Early
events of secondary degeneration after partial optic nerve transection: an
immunohistochemical study. J Neurotrauma. 2010
Feb;27(2):439-52. doi: 10.1089/neu.2009.1112. PubMed PMID: 19852581.
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Fitzgerald
M, Payne SC, Bartlett CA, Evill L, Harvey AR, Dunlop SA. Secondary retinal ganglion cell death and the
neuroprotective effects of the calcium channel blocker lomerizine. Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5456-62. doi: 10.1167/iovs.09-3717.
Epub 2009 May 27. PubMed PMID: 19474405.
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Fitzgerald
M, Bartlett CA, Evill L, Rodger J, Harvey AR, Dunlop SA. Secondary degeneration of the optic nerve following
partial transection: the benefits of lomerizine. Exp
Neurol. 2009 Mar;216(1):219-30. doi: 10.1016/j.expneurol.2008.11.026. Epub 2008
Dec 11. PubMed PMID: 19118550.
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Haustead DJ,
Lukehurst SS, Clutton GT, Bartlett CA, Dunlop SA, Arrese CA, Sherrard RM,
Rodger J. Functional
topography and integration of the contralateral and ipsilateral
retinocollicular projections of ephrin-A-/- mice. J
Neurosci. 2008 Jul 16;28(29):7376-86. doi: 10.1523/JNEUROSCI.1135-08.2008.
PubMed PMID: 18632942.
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Fitzgerald
M, Nairn P, Bartlett CA, Chung RS, West AK, Beazley LD. Metallothionein-IIA promotes neurite growth via the
megalin receptor. Exp Brain Res. 2007 Nov;183(2):171-80.
Epub 2007 Jul 19. PubMed PMID: 17634932.
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Symonds AC,
King CE, Bartlett CA, Sauvé Y, Lund RD, Beazley LD, Dunlop SA, Rodger J. EphA5 and ephrin-A2 expression during optic nerve
regeneration: a 'two-edged sword'. Eur J Neurosci. 2007
Feb;25(3):744-52. PubMed PMID: 17328773.
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Beazley LD, Rodger
J, King CE, Bartlett CA, Taylor AL, Dunlop SA. Optic
nerve regeneration: molecular pre-requisites and the role of training.
Restoring vision after optic nerve injury. Adv Exp Med
Biol. 2006;572:389-95. Review. PubMed PMID: 17249601.
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Rodger J,
Symonds AC, Springbett J, Shen WY, Bartlett CA, Rakoczy PE, Beazley LD, Dunlop
SA. Eph/ephrin
expression in the adult rat visual system following localized retinal lesions:
localized and transneuronal up-regulation in the retina and superior
colliculus. Eur J Neurosci. 2005 Oct;22(8):1840-52.
PubMed PMID: 16262624.
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Rodger J,
Vitale PN, Tee LB, King CE, Bartlett CA, Fall A, Brennan C, O'Shea JE, Dunlop
SA, Beazley LD. EphA/ephrin-A
interactions during optic nerve regeneration: restoration of topography and
regulation of ephrin-A2 expression. Mol Cell Neurosci.
2004 Jan;25(1):56-68. PubMed PMID: 14962740.
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Rodger J,
Bartlett CA, Harman AM, Thomas C, Beazley LD, Dunlop SA. Evidence that regenerating optic axons maintain long-term
growth in the lizard Ctenophorus ornatus: growth-associated protein-43 and
gefiltin expression. Neuroscience. 2001;102(3):647-54.
PubMed PMID: 11226701.
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Rodger J,
Bartlett CA, Beazley LD, Dunlop SA. Transient
up-regulation of the rostrocaudal gradient of ephrin A2 in the tectum coincides
with reestablishment of orderly projections during optic nerve regeneration in
goldfish. Exp Neurol. 2000 Nov;166(1):196-200. PubMed
PMID: 11031096.
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Nona SN,
Thomlinson AM, Bartlett CA, Scholes J. Schwann
cells in the regenerating fish optic nerve: evidence that CNS axons, not the
glia, determine when myelin formation begins. J
Neurocytol. 2000 Apr;29(4):285-300. PubMed PMID: 11276180.