Education
Ph.D., Imperial College, London, 2007
Lab information
https://www.msd-uk.com/research/discovery-centre.xhtml
Publications
Gillotin, S., Davies, J. D. and Philpott, A. (2018). Subcellular localisation modulates ubiquitylation and degradation of Ascl1.Sci Rep 8(1): 4625.
Gillotin, S. and Guillemot, F. (2016). Micro-chromatin Immunoprecipation(muChIP)Protocol for Real-time PCR Analysis of a Limited Amount of Cells.Bio Protoc 6(12).
Raposo, A. A., Vasconcelos, F. F., Drechsel, D., Marie, C., Johnston, C., Dolle, D., Bithell, A., Gillotin, S., vanden Berg, D. L., Ettwiller, L., Flicek, P., Crawford, G. E., Parras, C. M., Berninger, B., Buckley, N. J., Guillemot, F. and Castro, D. S. (2015).Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis.Cell Rep.
Masserdotti, G., Gillotin, S., Sutor, B., Drechsel, D., Irmler, M., Jorgensen, H. F., Sass, S., Theis, F. J., Beckers, J., Berninger, B., Guillemot, F. and Gotz, M. (2015).Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes.Cell Stem Cell 17(1): 74-88.
Gillotin, S. and Lu, X. (2011).The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53.FEBS Lett585(12): 1778-1782.
Gillotin, S., Yap, D. and Lu, X. (2010).Mutation at Ser392 specifically sensitizes mutant p53H175 to mdm2-mediated degradation.Cell Cycle 9(7): 1390-1398.
Gillotin, S. (2009). iASPP,a potential drug target in cancer therapy.Leuk Res 33(9): 1175-1177.
Slee, E. A., Gillotin, S., Bergamaschi, D., Royer, C., Llanos, S., Ali, S., Jin, B., Trigiante, G. and Lu, X. (2004). The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization.Oncogene 23(56): 9007-9016.