Viruses

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    Protocols in Current Issue
    Enterovirus Competition Assay to Assess Replication Fitness
    Authors:  Valeria Lulla and Andrew E. Firth, date: 05/20/2019, view: 857, Q&A: 0
    [Abstract] In virology the difference between the fitness of two viruses can be determined by using various methods, such as virus titer, growth curve analysis, measurement of virus infectivity, analysis of produced RNA copies and viral protein production. However, for closely performing viruses, it is often very hard to distinguish the differences. In vitro ...
    In vitro Assay to Assess Efficacy of Potential Antiviral Compounds against Enterovirus D68
    Authors:  Liang Sun, Leen Delang, Carmen Mirabelli and Johan Neyts, date: 03/20/2017, view: 4861, Q&A: 0
    [Abstract] In 2014 enterovirus D68 (EV-D68) caused the largest outbreak in the United States since the discovery of the virus. Distinct from before, the 2014 infections were associated with more severe respiratory disease and occasional neurological complications. So far, there are no available vaccines or antivirals for the prophylaxis or treatment of ...
    Enterovirus 71 Virus Propagation and Purification
    Authors:  Kristin L. Shingler, Lindsey J. Organtini and Susan Hafenstein, date: 05/05/2014, view: 9578, Q&A: 0
    [Abstract] Since its discovery in 1969, enterovirus 71 (EV71) has emerged as a serious worldwide health threat. This member of the picornavirus family causes hand, foot, and mouth disease, and also has the capacity to invade the central nervous system to cause severe disease and death. This is the propagation and purification procedure to produce infectious ...



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