Induced Germinal Center B Cell Culture System
Authors: Kei Haniuda and
Daisuke Kitamura,
date: 02/20/2019,
view: 8194,
Q&A: 0
[Abstract] The germinal center (GC) is the site where B cells undergo clonal expansion, affinity-based selection, and differentiation into memory B cells or plasma cells. It has been difficult to elucidate regulatory mechanisms for the dynamic GC B cell maturation and differentiation, partly because experimental manipulation of GC B cells in vivo ...